DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss46

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_898926.2	Gene:	Prss46 / 74306	MGIID:	1921556	Length:	314	Species:	Mus musculus

Alignment Length:	304	Identity:	80/304 - (26%)
Similarity:	128/304 - (42%)	Gaps:	54/304 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 TTPRPPSGIDQLP--EHPY---CGSA-FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGAS 165
            ::|...:.::.||  |.|:   ||.. .:.::|.|....:.::||...:.:..:     |.|..|
Mouse    13 SSPLASARLNSLPYMEGPWIWSCGQTNITCKVVNGKAVEVGKWPWQVSILFLGM-----YICSGS 72

  Fly   166 FIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQY 230
            .|...|:||||||:. ..:| .|....:....|.||     |...|       :.:.||:.|..:
Mouse    73 LIHHHWILTAAHCLQ-RSKN-PAKYTVKVGVQTLPD-----NSTSE-------LLVTRIVIHENF 123

  Fly   231 SELNYRNDIALLRLSRPVNWLQMQNLEPVCLP-----PQRGRYANQLAGSAADVSGWGKTESSGS 290
            .. ...:|||:|:|..||.|..:  ::|:|||     |.        .|:...|.|||..::.|.
Mouse   124 IN-RMSDDIAILKLKYPVTWSPL--VQPICLPSFNLKPS--------IGTMCWVVGWGLEKAEGH 177

  Fly   291 SKIK---QKAMLHIQPQDQCQEAF----YKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEAN 348
            .|..   |...:.|...:.|...:    .|:.|..:.:..:|...|.|:|:|...||..|..:.|
Mouse   178 PKTPYSVQGLAVRIVNNEICNHRYQFLLLKNQKKFIGNDMLCTSSEWGLDTCQDTSGSSLVCQMN 242

  Fly   349 TASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
                ..:|.: |||| ....||...|..:||..|.:..||:..|
Mouse   243 ----KTWVQM-GVVS-WNFDCGRRQFPSVYTSTSHFTQWIKRQI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	70/268 (26%)
		Tryp_SPc	133..391	CDD:238113	72/269 (27%)
Prss46	NP_898926.2	Tryp_SPc	43..276	CDD:214473	70/268 (26%)
Prss46	NP_898926.2	Tryp_SPc	44..279	CDD:238113	72/270 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910