DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss57

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001036175.1	Gene:	Prss57 / 73106	MGIID:	1920356	Length:	284	Species:	Mus musculus

Alignment Length:	321	Identity:	75/321 - (23%)
Similarity:	120/321 - (37%)	Gaps:	79/321 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LPRTTPRPP--------------SGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETV 154
            :|.:|...|              :.:.||...|.|..::   :||||.......|:...:.:|
Mouse     1 MPSSTAMVPGTRGGWHCLVLTTAAALTQLMWLPGCCGSY---IVGGHEVTPHSRPYMASVSFE-- 60

  Fly   155 SGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRV 219
              |..| ||...|...|:::||||......::...:||             .:.:....|.....
Mouse    61 --GHHY-CGGFLIHTHWVVSAAHCFSDRDPSMGLVVLG-------------AHALLAPEPTQQTF 109

  Fly   220 TIDRILPHAQYSELNYRNDIALLRLS------RPVNWLQM--QNLEPVCLPPQRGRYANQLAGSA 276
            :|...:.|..:......|||.||||:      ..|..|::  :|.:|            ..||:.
Mouse   110 SIAAAVSHPDFQPATQANDICLLRLNGSAVLGPAVRLLRLPRRNAKP------------PAAGTR 162

  Fly   277 ADVSGWG-----KTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMC--AGGEIGVDS 334
            ..|||||     :....|..:::    :.|.....|..::...    |..:.:|  :|.......
Mouse   163 CHVSGWGFVSDFEEPPPGLMEVE----VRILDLSVCNSSWQGQ----LNPAMLCTHSGDRRRRGF 219

  Fly   335 CSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            ||.||||||      ..|.|   ..|:||.....||......:||:||:::.||...:||:
Mouse   220 CSADSGGPL------VCGRR---AHGLVSFSGLWCGDPKTPDVYTQVSAFVTWIWDVVRAS 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	64/271 (24%)
		Tryp_SPc	133..391	CDD:238113	66/272 (24%)
Prss57	NP_001036175.1	Tryp_SPc	40..264	CDD:238113	64/270 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910