DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Prss41

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_036016678.1	Gene:	Prss41 / 71003	MGIID:	1918253	Length:	353	Species:	Mus musculus

Alignment Length:	345	Identity:	97/345 - (28%)
Similarity:	144/345 - (41%)	Gaps:	94/345 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCG--SAFSFRLVGGHNTGLFEF 143
            |.|.|.....:..|...:|.:|||            .:|    ||  :....|:|||..:....:
Mouse    47 PYLHPGSREESQAADLKSTDIKLL------------SMP----CGRRNDTRSRIVGGIESMQGRW 95

  Fly   144 PWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHT-MGRNLTAAILGE-------WNRDTDP 200
            ||...|..:     |.:.||.|.:::||:||||||... :........||:       |||..
Mouse    96 PWQASLRLK-----KSHRCGGSLLSRRWVLTAAHCFRKYLDPEKWTVQLGQLTSKPSYWNRKA-- 153

  Fly   201 DCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQR 265
                 .:|         |..:..|:.::: .:|. .:|:|||||:..|.:  .::::|||:.|..
Mouse   154 -----YSG---------RYRVKDIIVNSE-DKLK-SHDLALLRLASSVTY--NKDIQPVCVQPST 200

  Fly   266 GRYANQLAGSAADVSGWGKTESSGSSKIK--------QKAMLHIQPQDQCQEAF---------YK 313
            ....:|   ....|:|||..:..    :|        ::..:.|....:|||.|         .|
Mouse   201 FTSQHQ---PRCWVTGWGVLQED----LKPLPPPYHLREVQVSILNNSRCQELFEIFSLHHLITK 258

  Fly   314 DTKITLADSQMCAGGEIG-VDSCSGDSGGPLTVEANTASGNRYVYLAGVVS--IGRKHCGTALFS 375
            |.        .|||.|.| .|:|||||||||     ..:.:...|..|:||  ||   ||.....
Mouse   259 DV--------FCAGAEDGSADTCSGDSGGPL-----VCNMDGLWYQIGIVSWGIG---CGRPNLP 307

  Fly   376 GIYTRVSSYMDWIESTIRAN 395
            ||||.||.|.:|||:.:..|
Mouse   308 GIYTNVSHYYNWIETMMILN 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	82/284 (29%)
		Tryp_SPc	133..391	CDD:238113	84/285 (29%)
Prss41	XP_036016678.1	Tryp_SPc	84..321	CDD:238113	82/284 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910