DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss56

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006529921.1	Gene:	Prss56 / 69453	MGIID:	1916703	Length:	605	Species:	Mus musculus

Alignment Length:	355	Identity:	102/355 - (28%)
Similarity:	146/355 - (41%)	Gaps:	77/355 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PLAPRISNGTTNATSS--TTTLKLLPRTT------------------------PRPPSGIDQLPE 120
            ||..|:|.|.....|:  |..|:...|:.                        |||.:.:.|.|.
Mouse    24 PLYTRLSPGALQVLSAQGTQALQAAQRSAQWAIKRVLMEIQHRLHECQVGPGRPRPQAPLLQDPP 88

  Fly   121 HP-YCGSAFS---------FRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTA 175
            .| .||....         .|:|||.......:||...|:.    ||.. .||...:|..|:|||
Mouse    89 EPVQCGERHQGVANTTRAHGRIVGGSTAPSGAWPWLVRLQL----GGLP-LCGGVLVAASWVLTA 148

  Fly   176 AHCIHTMGRNLT-AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDI 239
            |||.......|. ..:|.|..:....:                .|.::|||||.::....:.||:
Mouse   149 AHCFAGASNELLWTVMLAEGPQGEQAE----------------EVQVNRILPHPKFDPQTFHNDL 197

  Fly   240 ALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKT-ESSGSSKIKQKAMLHIQP 303
            ||::|..||:  ......|:|| ||..|  ...||:...::|||.. |....|:..::|.:.:..
Mouse   198 ALVQLWTPVS--PEGPARPICL-PQGSR--EPPAGTPCAIAGWGALFEDGPESEAVREARVPLLS 257

  Fly   304 QDQCQEAFYKDTKITLADSQMCAG---GEIGVDSCSGDSGGPLTVEANTASGNR-YVYLAGVVSI 364
            .|.||:......:   ..:.:|||   |  |:|||.||||||||.   :..|.| ...|.||.|.
Mouse   258 ADTCQKVLGPGLR---PSTMLCAGYLAG--GIDSCQGDSGGPLTC---SEPGPRPREVLFGVTSW 314

  Fly   365 GRKHCGTALFSGIYTRVSSYMDWIESTIRA 394
            | ..||.....|:||||:.:.||::..:.|
Mouse   315 G-DGCGEPGKPGVYTRVTVFKDWLQEQMSA 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/262 (32%)
		Tryp_SPc	133..391	CDD:238113	83/263 (32%)
Prss56	XP_006529921.1	Tryp_SPc	109..336	CDD:214473	82/261 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910