DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss55

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_008769022.1	Gene:	Prss55 / 683415	RGDID:	1586875	Length:	321	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	79/266 - (29%)
Similarity:	122/266 - (45%)	Gaps:	44/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM---GRNLTAAILG 192
            |::||....:.||||..     ::.....:.||.|.:::.|:||.|||.::.   ...||..:
  Rat    34 RIIGGQEAEVGEFPWQV-----SIQENDHHFCGGSILSEWWILTVAHCFYSQELSPTELTVRV-- 91

  Fly   193 EWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLE 257
                     ..|||.    .:|..::||  .|:.|..:...:..||||||.|:.|:.:  .:...
  Rat    92 ---------GTNDLT----TSPMELQVT--NIIRHKDFKRHSMDNDIALLLLANPLTF--NEQTV 139

  Fly   258 PVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK---QKAMLHIQPQDQCQEAFYKDTKITL 319
            |:|:|.|    ....:.....|:|||.|.|:....:.   .|..:.|....:|.:.|     .:|
  Rat   140 PICMPLQ----PTPPSWQECWVAGWGTTNSADKESMNMDLMKVPMRITDWKECLQLF-----PSL 195

  Fly   320 ADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSS 383
            ..:.:||. |....|:|.|||||||.  .|..|..|: |..|::|.| |.||.....||||.:::
  Rat   196 TTNMLCASYGNESFDACQGDSGGPLV--CNQESDGRW-YQVGIISWG-KSCGQKGSPGIYTVLAN 256

  Fly   384 YMDWIE 389
            |:.|||
  Rat   257 YILWIE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/263 (29%)
		Tryp_SPc	133..391	CDD:238113	78/264 (30%)
Prss55	XP_008769022.1	Tryp_SPc	35..264	CDD:238113	78/265 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910