DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss41

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001128559.1	Gene:	Prss41 / 681033	RGDID:	1584711	Length:	324	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	92/320 - (28%)
Similarity:	139/320 - (43%)	Gaps:	80/320 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 TTLKLLPRTTPRPPSGIDQLPEHPYCG--SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYA 161
            |.:|||            .:|    ||  :....|:|||..:....:||...|...     |.:.
  Rat    36 TDIKLL------------SMP----CGRRNDIRSRIVGGIESVRGRWPWQASLRLR-----KFHR 79

  Fly   162 CGASFIAQRWLLTAAHCIHT-MGRNLTAAILGE-------WNRDTDPDCENDLNGVRECAPPHIR 218
            ||.|.::.||:||||||... :........||:       |||:.       .:|         |
  Rat    80 CGGSLLSHRWVLTAAHCFRKFLDPKKWTVQLGQLTSKPSFWNREA-------FSG---------R 128

  Fly   219 VTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWG 283
            ..:..|:.::: .:|.| :|:|||||:..|.:.:.  ::|||:.|......:|   ....|:|||
  Rat   129 YRVKDIIINSE-DKLKY-HDLALLRLASSVTYNKF--IQPVCVLPSASMSQHQ---PRCWVTGWG 186

  Fly   284 KTESSGSSKIK-----------QKAMLHIQPQDQCQEAFYKDTKITLADSQM-CAGGEIG-VDSC 335
            ..:..    :|           |..:|::   .:|||.|...::..|....: |||.|.| .|:|
  Rat   187 ALQED----LKPLPPPYHLREVQVTVLNL---SRCQELFSFASRYHLITRDVFCAGAEDGSADTC 244

  Fly   336 SGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            ||||||||     ..:.:...|..|:||.| ..||.....||||.||.:.|||::.:..|
  Rat   245 SGDSGGPL-----VCNMDGLWYQIGIVSRG-VGCGRPKLPGIYTNVSHHYDWIKTMMILN 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	82/277 (30%)
		Tryp_SPc	133..391	CDD:238113	83/278 (30%)
Prss41	NP_001128559.1	Tryp_SPc	54..291	CDD:214473	82/277 (30%)
Prss41	NP_001128559.1	Tryp_SPc	55..292	CDD:238113	82/277 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910