DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and f9b

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	321	Identity:	97/321 - (30%)
Similarity:	148/321 - (46%)	Gaps:	51/321 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NGTT-NATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFS-----FRLVGGHNTGLFEFPWTT 147
            |||. |.|.|:.|......:|..|.:.:..:...|...:..:     :|:|||......|.||..
Zfish   207 NGTEYNTTESSPTDLSEMNSTSTPRNSLQNVSSSPILTNINNTTNNKYRIVGGDEAIPGEIPWQV 271

  Fly   148 LLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAI-LGEWNRDTDPDCENDLNGVRE 211
            :. .|.|:  |...||.|.:::.|::|||||:.  |:..:..| :||.:.......|:| :|:.|
Zfish   272 VF-LEKVN--KIVFCGGSLLSEEWVITAAHCVE--GKQGSFFIRVGEHDVSKMEGTESD-HGIEE 330

  Fly   212 CAPPHIRVTIDRILPHAQYSELN--YRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAG 274
            .   ||         |.:|:...  |.:|||||:|.:||  :......|:||..:  .:...|..
Zfish   331 Y---HI---------HPRYNSQRSLYNHDIALLKLKKPV--ILFDYAVPICLGSK--DFTENLLQ 379

  Fly   275 SAAD--VSGWGKTESSG-SSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSC 335
            ||.:  |||||:....| .|.:.||..|....:.:|:.:    :..:::....||| ..:..|:|
Zfish   380 SAENSLVSGWGRLRYGGIESNVLQKVELPYVDRIKCKGS----STDSISRFMFCAGYSTVRKDAC 440

  Fly   336 SGDSGGPLTVEANTASGNRYV---YLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIR 393
            .||||||        ...||.   :|.|:||.| :.|......|||||:|.||.||.:..|
Zfish   441 QGDSGGP--------HATRYKDTWFLTGIVSWG-EECAKEGKYGIYTRISKYMAWITNITR 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	84/266 (32%)
		Tryp_SPc	133..391	CDD:238113	85/267 (32%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342
		Tryp_SPc	255..487	CDD:214473	84/266 (32%)
		Tryp_SPc	256..490	CDD:238113	85/268 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910