DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and 2210010C04Rik

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_075822.3	Gene:	2210010C04Rik / 67373	MGIID:	1914623	Length:	247	Species:	Mus musculus

Alignment Length:	278	Identity:	85/278 - (30%)
Similarity:	121/278 - (43%)	Gaps:	67/278 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWN 195
            ::|||:.......|:...|.    ||  .:.||.|.|..:|:::||||.    ::.....|||.|
Mouse    24 KIVGGYTCQRNALPYQVSLN----SG--YHFCGGSLINSQWVVSAAHCY----KSRIQVRLGEHN 78

  Fly   196 RDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRL--SRPVNWLQMQNLEP 258
            .|.       |.|..:.      :...:|:.|..|:...|.|||.|::|  :..:|    ..:..
Mouse    79 IDA-------LEGGEQF------IDAAKIIRHPNYNANTYNNDIMLIKLKTAATLN----SRVST 126

  Fly   259 VCLP---PQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA-FYKDTKIT- 318
            |.||   |.        ||:...|||||.|.|||::   ..::|      ||.:| ...|:..|
Mouse   127 VALPRSCPS--------AGTRCLVSGWGNTLSSGTN---YPSLL------QCLDAPVLSDSSCTS 174

  Fly   319 -----LADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGI 377
                 :..:..|.|. |.|.|||.||||||:.....         |.||||.| ..|......|:
Mouse   175 SYPGKITSNMFCLGFLEGGKDSCQGDSGGPVVCNGQ---------LQGVVSWG-YGCAQRGKPGV 229

  Fly   378 YTRVSSYMDWIESTIRAN 395
            ||:|..|::||:.||.||
Mouse   230 YTKVCKYVNWIQQTIAAN 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	79/269 (29%)
		Tryp_SPc	133..391	CDD:238113	81/270 (30%)
2210010C04Rik	NP_075822.3	Tryp_SPc	24..240	CDD:214473	79/269 (29%)
2210010C04Rik	NP_075822.3	Tryp_SPc	25..243	CDD:238113	81/271 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910