DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Klk13

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001034131.2	Gene:	Klk13 / 626834	MGIID:	3615275	Length:	276	Species:	Mus musculus

Alignment Length:	330	Identity:	96/330 - (29%)
Similarity:	129/330 - (39%)	Gaps:	110/330 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLL 149
            |:|.|| ||.||...            |.|...||                |:.     ||...|
Mouse    24 PKILNG-TNGTSGFL------------PGGYTCLP----------------HSQ-----PWQAAL 54

  Fly   150 EYETVSGGKDYACGASFIAQRWLLTAAHC----------IHTMGRNLTAAILGEWNRDTDPDCEN 204
               .:.|  ...||...:..:|:||||||          .|.:||                 .||
Mouse    55 ---LIRG--RLLCGGVLVHPKWVLTAAHCRKDGYTVHLGKHALGR-----------------VEN 97

  Fly   205 DLNGVRECAPPHIRVTIDRILPHAQY----SELNYRNDIALLRLSRPVNW-LQMQNLE---PVCL 261
            ....:.          :.|.:||.:|    :.||:.:||.||.|..||.. ..::.|:   ..||
Mouse    98 GEQAME----------VVRSIPHPEYQVTPTHLNHDHDIMLLELKSPVQLSSHVRTLKLSADDCL 152

  Fly   262 PPQRGRYANQLAGSAADVSGWGKTESS--GSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQM 324
            |          .|:...|||||.|.|.  ...|..|.|.:.::..::|::.:  ..|||.  :.:
Mouse   153 P----------TGTCCRVSGWGTTTSPQVNYPKTLQCANIELRSDEECRQVY--PGKITA--NML 203

  Fly   325 CAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            ||| .|.|.|||.|||||||     ..:|..|    |::|.|...||.....|:|||||.|:.||
Mouse   204 CAGTKEGGKDSCEGDSGGPL-----ICNGKLY----GIISWGDFPCGQPNRPGVYTRVSKYLRWI 259

  Fly   389 ESTIR 393
            ...||
Mouse   260 REIIR 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/277 (29%)
		Tryp_SPc	133..391	CDD:238113	82/278 (29%)
Klk13	NP_001034131.2	Tryp_SPc	39..262	CDD:238113	85/298 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910