DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and Prss21

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_065233.2	Gene:	Prss21 / 57256	MGIID:	1916698	Length:	324	Species:	Mus musculus

Alignment Length:	302	Identity:	97/302 - (32%)
Similarity:	136/302 - (45%)	Gaps:	59/302 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PEHPY----------CG-SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWL 172
            ||.|.          || .....|:|||.:..|..:||...|.   |.|  ::.|||:.:.:||:
Mouse    31 PEKPELQEPDLLSGPCGHRTIPSRIVGGDDAELGRWPWQGSLR---VWG--NHLCGATLLNRRWV 90

  Fly   173 LTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPP-------HIRVTIDRILPHAQY 230
            ||||||               :.:|.||.......|.....|.       ..|..|:.|....:|
Mouse    91 LTAAHC---------------FQKDNDPFDWTVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKY 140

  Fly   231 SELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGW---GKTESSGSSK 292
            || .|.||||||:||.||.:...  ::|:||.....::.|:   :...|:||   |:.||..|..
Mouse   141 SE-QYPNDIALLKLSSPVTYNNF--IQPICLLNSTYKFENR---TDCWVTGWGAIGEDESLPSPN 199

  Fly   293 IKQKAMLHIQPQDQCQEAFYK-DTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRY 355
            ..|:..:.|.....|...:.| |.:..:....:||| .|.|.|:|.|||||||..:.:|.
Mouse   200 TLQEVQVAIINNSMCNHMYKKPDFRTNIWGDMVCAGTPEGGKDACFGDSGGPLACDQDTV----- 259

  Fly   356 VYLAGVVS--IGRKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            .|..||||  ||   ||.....|:||.:|.:.:||:||:..|
Mouse   260 WYQVGVVSWGIG---CGRPNRPGVYTNISHHYNWIQSTMIRN 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	87/270 (32%)
		Tryp_SPc	133..391	CDD:238113	88/271 (32%)
Prss21	NP_065233.2	Tryp_SPc	54..291	CDD:214473	87/270 (32%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	88/272 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910