DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP001249

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001689375.2	Gene:	AgaP_AGAP001249 / 5667667	VectorBaseID:	AGAP001249	Length:	267	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	77/257 - (29%)
Similarity:	117/257 - (45%)	Gaps:	41/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILG 192
            ::.|:|||....:.:||:...|..     ..::.||||.|:..|.|:||||...|....:.:..|
Mosquito    38 YNGRIVGGSTVPISQFPYQLSLRQ-----NGNHICGASVISSNWALSAAHCTFPMPSAASISFRG 97

  Fly   193 EWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLE 257
            ..:..|.       .||...|.        :|:.|.||:..|..||:.::|::..   ....|:.
Mosquito    98 GSDSRTG-------GGVIFQAA--------QIINHPQYNSNNLNNDVCVIRITTS---FVGANIA 144

  Fly   258 PVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAM-LHIQPQDQCQEAFYKDTKITLAD 321
            |:.|......:|   ||:.:.|||||.|...||..:...|: :.:..|..|... :...:||.|
Mosquito   145 PIRLVASGTSFA---AGTNSVVSGWGLTSPGGSLPVNLHAVNIPVVAQATCSSQ-WGTGRITAA- 204

  Fly   322 SQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSS 383
             .:|||.: |.|||:|||||||     ...|.::    ||||.|...||..| .|:|..:.:
Mosquito   205 -MVCAGVQ-GRDSCNGDSGGPL-----VTGGAQF----GVVSWGAVQCGGPL-PGVYANIGN 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/254 (30%)
		Tryp_SPc	133..391	CDD:238113	76/252 (30%)
AgaP_AGAP001249	XP_001689375.2	Tryp_SPc	41..254	CDD:214473	77/252 (31%)
AgaP_AGAP001249	XP_001689375.2	Tryp_SPc	42..264	CDD:238113	76/253 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910