DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005596

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001688689.1	Gene:	AgaP_AGAP005596 / 5666841	VectorBaseID:	AGAP005596	Length:	266	Species:	Anopheles gambiae

Alignment Length:	261	Identity:	55/261 - (21%)
Similarity:	96/261 - (36%)	Gaps:	73/261 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAH-CIH-------TMGRNLTAAILGEWNRDT 198
            :||:.|.:|...|      .|..:.|...::::.|. |::       ..|..:.|.....|.:
Mosquito    56 QFPYLTFIENNGV------VCNGALITPNYIVSVARGCLNRSTIKTAQYGTAILAFNKNMWEQ-- 112

  Fly   199 DPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPP 263
                                    ||...|....|:...||||.||:.|..  ..::::|:.||
Mosquito   113 ------------------------RINFSASAINLHPYEDIALARLNYPAT--LNKHVQPIRLP- 150

  Fly   264 QRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG 328
                   :|:.|.:.|...|.|.:: :..::.:.|.:.    :|.:. :.:...|..|  :|...
Mosquito   151 -------KLSDSRSYVDMEGTTVAT-NRYVRNRVMSNA----ECTKE-HPNFNATHVD--ICTDR 200

  Fly   329 EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKH----CGTALFSGIYTRVSSYMDWIE 389
            ..|...||...|.|||:|...          ||:.||..:    |.....:| |.|:..:.|||.
Mosquito   201 YKGGAFCSFFLGSPLTIEDEN----------GVILIGLANWISSCDNNYPTG-YARILPFRDWIH 254

  Fly   390 S 390
            :
Mosquito   255 N 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	53/257 (21%)
		Tryp_SPc	133..391	CDD:238113	55/261 (21%)
AgaP_AGAP005596	XP_001688689.1	Tryp_SPc	54..256	CDD:304450	55/261 (21%)
AgaP_AGAP005596	XP_001688689.1	Tryp_SPc	54..253	CDD:214473	53/257 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910