DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and f10

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	436	Identity:	112/436 - (25%)
Similarity:	187/436 - (42%)	Gaps:	122/436 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QFGKAIMHFGNCNSVEFGRGTCI-----EKKDCDFYAVDKLMELAS------KQQCFSRQRPDLV 71
            |:|      |:||. .....||:     |.|:|:...    ::|.|      .|.|.:..| |:|
Frog    95 QYG------GSCND-GINEYTCLCNAGFEGKNCETVK----LQLCSLNNGECDQYCKAVDR-DVV 147

  Fly    72 C-CP-----------------------------RETNIIPPLAPRISNGTTNATSSTTTLKL--- 103
            | |.                             |||.:       ..|...|.|.|...:|:
Frog   148 CSCTNGYILGENGKSCLPTEKYSCGRRHMKRERRETKL-------HENDKKNHTDSQNEVKMNQT 205

  Fly   104 --LPRTTPRPPSGIDQL-PEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGAS 165
              ||.   |..:||:.| |..|      :.|:|||......|.||..||    ||...:..||.:
Frog   206 GTLPE---RNVTGINILNPNDP------NVRIVGGRECSQGECPWQALL----VSDEDEGFCGGT 257

  Fly   166 FIAQRWLLTAAHCIHTMGRNLT---AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPH 227
            .:::.::||||||:     |.|   ..::||.|.......|:          .|   .:::|:.|
Frog   258 ILSREFILTAAHCM-----NQTKYFKVVVGELNTKISEGTES----------IH---KVEKIIMH 304

  Fly   228 AQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLP-PQRGRYANQLAGSAAD--VSGWGKTESSG 289
            .::.:..|..|||:::|...:|:  .:|:.|.|:| |:   :|:|:..:..|  |||:|:....|
Frog   305 PRFVKSTYDYDIAVIKLKEAINF--TENIIPACIPDPE---FADQVLMNEPDAMVSGFGRIHERG 364

  Fly   290 --SSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGV-DSCSGDSGGPLTVEANTAS 351
              :|.::...:.:|: :..|:|:    :...:.::..|||.:..| |:|.||||||   ......
Frog   365 RQASTLQMLQVPYIK-RHSCKES----STFAITENMFCAGFDTEVKDACQGDSGGP---HVTPFK 421

  Fly   352 GNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRANRI 397
            |..:|  .|:||.| :.|......|:||:||....|::..::.|::
Frog   422 GTYFV--TGIVSWG-EGCARKGKFGVYTKVSKLHRWLKGVLKKNQV 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	15/56 (27%)
		Tryp_SPc	131..388	CDD:214473	75/265 (28%)
		Tryp_SPc	133..391	CDD:238113	75/266 (28%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011	9/32 (28%)
		FXa_inhibition	128..163	CDD:373209	8/35 (23%)
		Tryp_SPc	228..456	CDD:238113	75/265 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010