DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Hgfac

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006504094.1	Gene:	Hgfac / 54426	MGIID:	1859281	Length:	658	Species:	Mus musculus

Alignment Length:	326	Identity:	91/326 - (27%)
Similarity:	146/326 - (44%)	Gaps:	69/326 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 TTLKLLPRTTPRPPSGIDQLPE-----HPYCGSAF---SF---RLVGGHNTGLFEFPWTTLLEYE 152
            |..:.|.|...:.|..:..|||     .|.||...   :|   |::||.::.....||...:..
Mouse   362 TACESLARVHSQTPEILAALPESAPAVRPTCGKRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI- 425

  Fly   153 TVSGGKDYACGASFIAQRWLLTAAHCI-HTMGRNLTAAILGE--WNRDTDPDCENDLNGVRECAP 214
                |..: |..|.:...|:::||||. ::..|:....:||:  :||.||
Mouse   426 ----GNSF-CAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTD--------------- 470

  Fly   215 PHIRVT----IDRILPHAQYSELNYRN-DIALLRLSRPVN--WLQMQNLEPVCLPPQRGRYANQL 272
                ||    |::.:|:..||..|..| |:.|:||.:...  .::.|.::|:|||.....:.
Mouse   471 ----VTQTFGIEKYVPYTLYSVFNPNNHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFP--- 528

  Fly   273 AGSAADVSGWG-------KTESSGSSKIKQKAMLHIQPQDQCQ--EAFYKDTKITLADSQMCAG- 327
            .|....::|||       .|:.|..|....:|::.:....:|.  |.:..|    ::.:.:|||
Mouse   529 TGHKCQIAGWGHMDEMQSSTDVSSYSNSLLEALVPLVADHKCSSPEVYGAD----ISPNMLCAGY 589

  Fly   328 GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            .:...|:|.|||||||..|.|..:     ||.|::|.| ..||.....|:||||::|:|||...|
Mouse   590 FDCKSDACQGDSGGPLVCEKNGVA-----YLYGIISWG-DGCGRLNKPGVYTRVANYVDWINDRI 648

  Fly   393 R 393
            |
Mouse   649 R 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/276 (28%)
		Tryp_SPc	133..391	CDD:238113	77/277 (28%)
Hgfac	XP_006504094.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF_CA	242..275	CDD:238011
		Kringle	283..364	CDD:333799	1/1 (100%)
		Tryp_SPc	406..646	CDD:238113	77/277 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910