DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and prss60.2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	308	Identity:	94/308 - (30%)
Similarity:	141/308 - (45%)	Gaps:	46/308 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 TSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSA-FSFRLVGGHNTGLFEFPWTTLLEYETVSGGK 158
            |.:|.||.:..:      ..:.||   ..||.| .:.|:|||.|.....:||...|:.....|
Zfish     5 TCATLTLLICVK------GSLSQL---NVCGQAPLNSRIVGGVNAPEGSWPWQVSLQSPRYGG-- 58

  Fly   159 DYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDR 223
             :.||.|.|:..|:||||||:..:..:.....||...:......|...|             :.:
Zfish    59 -HFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRTQQGVNTHETSRN-------------VAK 109

  Fly   224 ILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESS 288
            |:.|:.|:.....|||||||||..|.:  ...:.||||..|...|:   ||:::.::|||..::.
Zfish   110 IIVHSSYNSNTNDNDIALLRLSSAVTF--NDYIRPVCLAAQNSVYS---AGTSSWITGWGDVQAG 169

  Fly   289 ---GSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANT 349
               .:..|.|:.|:.:...|:|.......   |:.::.:||| .:.|.|:|.||||||:.....|
Zfish   170 VNLPAPGILQETMIPVVANDRCNAQLGSG---TVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCT 231

  Fly   350 ASGNRYVYL-AGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRANR 396
                  |:: ||:.|.| ..|......|:|||||.|..||.|.|..|:
Zfish   232 ------VWIQAGITSWG-YGCADPNSPGVYTRVSQYQSWISSKISQNQ 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/261 (31%)
		Tryp_SPc	133..391	CDD:238113	81/262 (31%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	80/261 (31%)
		Tryp_SPc	34..267	CDD:238113	81/263 (31%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910