DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038948844.1	Gene:	Tmprss11f / 498345	RGDID:	1560675	Length:	459	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	94/322 - (29%)
Similarity:	140/322 - (43%)	Gaps:	71/322 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGL-FEFPWT 146
            |.|..|....|..:|...:::.....|.|.|...:             |:|.|..|.: .|:||.
  Rat   191 LTPIDSKKMRNLLNSRCGIRMSSSNIPLPASSTTE-------------RIVQGRETAMEGEWPWQ 242

  Fly   147 TLLEYETVSGGKDYACGASFIAQRWLLTAAHC----------IHTMGRNLTAAILGEWNRDTDPD 201
            ..|:..    |..:.|||:.|:..||||||||          |.|.|..:|
  Rat   243 ASLQLI----GAGHQCGATLISNTWLLTAAHCFWKNRDPSKWIATFGTTIT-------------- 289

  Fly   202 CENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRG 266
                        ||.::.::.||:.|.:|...:..|||||.:|:..|.:..:  ::.||||....
  Rat   290 ------------PPLVKRSVGRIIIHEEYHRDSNENDIALAQLTSRVEFSNV--VQRVCLPDSSM 340

  Fly   267 RYANQLAGSAADVSGWGKTESSGSSKIK-QKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEI 330
            :...:   ::..|:|:|.....|.::.| ::|.:.....|.|.:....|..||  ...:|||...
  Rat   341 KLPPK---TSVFVTGFGSIVDDGPTQNKLRQARVETIGSDVCNQKDVYDGLIT--PGMLCAGFME 400

  Fly   331 G-VDSCSGDSGGPLTVEANTASGNRYV-YLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIES 390
            | ||:|.|||||||..:      ||.: |:.|:||.|:. |......|:|||||.|.|||.|
  Rat   401 GKVDACKGDSGGPLVYD------NRDIWYIVGIVSWGQS-CALPNKPGVYTRVSKYRDWIAS 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/270 (31%)
		Tryp_SPc	133..391	CDD:238113	85/272 (31%)
Tmprss11f	XP_038948844.1	SEA	80..185	CDD:396113
Tmprss11f	XP_038948844.1	Tryp_SPc	227..456	CDD:238113	85/273 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910