DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and prss27

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	81/288 - (28%)
Similarity:	130/288 - (45%)	Gaps:	50/288 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGS-AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC------IHT 181
            ||. |||.|:|||:|....|:||...:.|:     ..:.||.|.::..|:::||||      |..
Frog   411 CGQPAFSDRIVGGNNAVFGEWPWQVSIVYQ-----NSHICGGSLVSSNWVVSAAHCFPRSYKIEN 470

  Fly   182 MGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSR 246
            |     ..:||         |...:|...:.    :.:.:.|::.:..|:......|||::.:..
Frog   471 M-----QVLLG---------CFALMNLTSDA----VIIRVKRVITYPLYTGEGSSGDIAMVEMES 517

  Fly   247 PVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK---QKAMLHIQPQDQCQ 308
            ||.:  ...:.|:|:|.....:.   :|....|:|||..:|..|....   |:..:.:.....|.
Frog   518 PVTY--SSYILPICIPLTNEDFP---SGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCD 577

  Fly   309 EAFYKDTKITLA-----DSQMCAGGEIG-VDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRK 367
            ..::.::.:..|     |..:|||...| .|:|.|||||||..:    ||| |.:|.|:||.| .
Frog   578 TMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACK----SGN-YWFLTGIVSWG-D 636

  Fly   368 HCGTALFSGIYTRVSSYMDWIESTIRAN 395
            .|......|:||:|||:..||...:..|
Frog   637 GCAQPNRPGVYTKVSSFSSWINQYLVLN 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	73/271 (27%)
		Tryp_SPc	133..391	CDD:238113	74/272 (27%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	74/272 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910