DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and tll1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001008039.1	Gene:	tll1 / 493401	XenbaseID:	XB-GENE-479941	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	42/226 - (18%)
Similarity:	69/226 - (30%)	Gaps:	84/226 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 RISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLL- 149
            |:.:|.|     |:...:|.:|                ||:.....::...|..|.||...:.:
Frog   326 RVYDGAT-----TSAPMILDKT----------------CGTGPLPVMIASTNRMLVEFVTDSAIT 369

  Fly   150 ------EYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDP--DCENDL 206
                  .|.||.      ||.:|             :|..||:|..   .:.:...|  ||:..:
Frog   370 APGFKASYSTVQ------CGGTF-------------YTPSRNVTTP---NYPKSYPPNLDCQFII 412

  Fly   207 NGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYA-- 269
            .     ||...:|.            ||..|.......:...::|::.:...:..|....||.
Frog   413 T-----APTSYKVA------------LNINNFFVEKSANCQYDYLEIYDGNSMSAPKIGSRYCSY 460

  Fly   270 ---NQLAGSA----------ADVSGWGKTES 287
               |.:..|.          |.|..:|.|.|
Frog   461 QVFNVMVSSGRSMLLRFHSDASVQMYGFTAS 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	34/181 (19%)
		Tryp_SPc	133..391	CDD:238113	34/179 (19%)
tll1	NP_001008039.1	ZnMc_hatching_enzyme	83..265	CDD:239810
		CUB	269..379	CDD:238001	13/73 (18%)
		CUB	382..494	CDD:238001	27/143 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910