DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	264	Identity:	83/264 - (31%)
Similarity:	122/264 - (46%)	Gaps:	41/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDT--DPDC-- 202
            ||.....:.:....|..::.||.|.|...::||||||..              :|||  .||.
Mosquito    26 EFSAIAAIGWTKPGGTVNWNCGGSLIWANFILTAAHCTK--------------DRDTLLPPDIIR 76

  Fly   203 ENDLN--GVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVN-WLQMQNLEPVCLPPQ 264
            ..|||  ..||.|....| ||.|::.|..|:..:...|||||.|:..|| :.::.   |.||
Mosquito    77 IGDLNLYDDREDALVQER-TIIRVIRHPLYNTSSVFYDIALLMLNEKVNIYFEVM---PTCL--- 134

  Fly   265 RGRYANQLAGSAADVSGWGKTE-SSGSSKIKQKAMLHIQPQDQCQEAFYK---DTKITLADSQMC 325
              ...:.:..|..:.:|||.:. ..|.:.|..||.|.:.....| |::|.   ..|..|.:.|:|
Mosquito   135 --WLDDNIPFSKVEAAGWGTSGFGYGKTNILIKAELKLMANKDC-ESYYSQVASVKNGLMEHQLC 196

  Fly   326 AGGEIGVDSCSGDSGGPLTVEANTASGNRYV-YLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIE 389
            |..:: :|:|.|||||||  :.....|:..| :|.||.|.|.. ||.:. .|:|.:||.:..||.
Mosquito   197 AWDKV-MDTCPGDSGGPL--QHKLIFGDYKVPFLVGVTSFGLS-CGNSQ-PGVYVKVSKFGSWIV 256

  Fly   390 STIR 393
            .|::
Mosquito   257 ETLQ 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/257 (31%)
		Tryp_SPc	133..391	CDD:238113	82/260 (32%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	82/260 (32%)
		Tryp_SPc	19..255	CDD:214473	80/257 (31%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910