DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP010240

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001238153.2	Gene:	AgaP_AGAP010240 / 4578338	VectorBaseID:	AGAP010240	Length:	275	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	88/289 - (30%)
Similarity:	127/289 - (43%)	Gaps:	50/289 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 PPSGIDQLPEH---PYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWL 172
            ||....::...   |:..:..|.|:|.|....|.:||:...|     .|....|||.|.|:..|:
Mosquito    20 PPQNAREISYQSIVPFREATRSSRIVNGFPASLGQFPYQVFL-----IGDGSLACGGSLISAEWV 79

  Fly   173 LTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRN 237
            ||||||  .:|.:......|        ..:|:..|.       :| |.:.|:.|..|:..|..|
Mosquito    80 LTAAHC--QVGISQFTVRAG--------SIQNNSGGT-------VR-TSNLIIIHPNYNPSNLNN 126

  Fly   238 DIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKT-ESSGS-SKIKQKAMLH 300
            ||.|:||:.|:.  ...|::.|.||  ....:.......|.|||:|:| ::||: |.......|:
Mosquito   127 DIGLIRLNEPMP--LGGNIQVVALP--EANLSETFLNREATVSGFGRTSDASGAISPNLNFVHLN 187

  Fly   301 IQPQDQCQEAFYKDTKITLADSQMCAGGEIGVD-----SCSGDSGGPLTVEANTASGNRYVYLAG 360
            |....||...:   ...|:.||.:||   :|.|     :|:|||||||||..|..|     ...|
Mosquito   188 IISNIQCMGTY---GSATIIDSTVCA---VGRDAPNQGTCNGDSGGPLTVTENGQS-----VQIG 241

  Fly   361 VVS-IGRKHCGTALFSGIYTRVSSYMDWI 388
            ||| :....|.....|| |.|.:.:.:||
Mosquito   242 VVSFVAAAGCEVGFPSG-YVRTTHFRNWI 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	82/264 (31%)
		Tryp_SPc	133..391	CDD:238113	83/264 (31%)
AgaP_AGAP010240	XP_001238153.2	Tryp_SPc	43..269	CDD:214473	82/264 (31%)
AgaP_AGAP010240	XP_001238153.2	Tryp_SPc	44..272	CDD:238113	83/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910