DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005587

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001237684.2	Gene:	AgaP_AGAP005587 / 4576204	VectorBaseID:	AGAP005587	Length:	296	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	59/257 - (22%)
Similarity:	91/257 - (35%)	Gaps:	53/257 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 EFPWTTLLEYETVSGGKDY-----ACGASFIAQRWLLTAAHCI--HTMGRNLTAAILGEWNRDTD 199
            :||:..|: |......|.:     ....|.|...::||:|..:  :.:|...|...:....|
Mosquito    73 QFPYHALV-YINNENPKPWESSIVQTAGSLITPNYILTSAEVLRKNILGNGKTYGFVELGYR--- 133

  Fly   200 PDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQ 264
                   ||........|..|...|..|.::|...:.| ||.:||..|..  ..:.::|:.||
Mosquito   134 -------NGADRERQQVIDFTNSSISIHPRFSGGLFYN-IATIRLEHPAT--LNRYVQPIRLP-- 186

  Fly   265 RGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGE 329
              |.::.......:.:..|. ..:|:.:..:..:|   |.|.|           |....:|....
Mosquito   187 --RLSDNRTFEMMEGTSLGH-HYNGTMRYMRNQVL---PHDNC-----------LLQEYVCTNSF 234

  Fly   330 IGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIG---RKHCGTALFSGIYTRVSSYMDWI 388
            ||...|:...|..||||...          |.:.||   |.:........|.||||.|.|||
Mosquito   235 IGGAFCNRVDGAGLTVEDED----------GPILIGFTMRVYWCDLNERDINTRVSVYRDWI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	57/255 (22%)
		Tryp_SPc	133..391	CDD:238113	59/257 (23%)
AgaP_AGAP005587	XP_001237684.2	Tryp_SPc	54..286	CDD:214473	57/255 (22%)
AgaP_AGAP005587	XP_001237684.2	Tryp_SPc	66..289	CDD:304450	59/257 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910