DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP000411

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001237291.3	Gene:	AgaP_AGAP000411 / 4576124	VectorBaseID:	AGAP000411	Length:	1091	Species:	Anopheles gambiae

Alignment Length:	270	Identity:	69/270 - (25%)
Similarity:	121/270 - (44%)	Gaps:	40/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 VGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAI----LGE 193
            :.||      :||...: :......|:||||.|.:.:..:|||:||:.|:...::||:    :|:
Mosquito    30 IAGH------WPWHAAI-FHQKDKHKEYACGGSILDETTILTASHCVSTLSGVISAALVTVHVGQ 87

  Fly   194 WNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEP 258
            .:.:...:...... .||            |:.:..:|:.:..:||||::|.  .|....:.::|
Mosquito    88 IHLNQSSEYTQTFE-ARE------------IIINPGFSKASIIHDIALIKLR--TNISMNRYVQP 137

  Fly   259 VCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQC--QEAFYKDTKITLAD 321
            |||...... ...:.|....:.|:|.:|....|:..::|.:.:.....|  .:.....|.:||
Mosquito   138 VCLWTMDSA-LELIVGRNGTIVGFGLSERDVVSEQLKQATIGVVDPYTCIASDRVVYGTHLTL-- 199

  Fly   322 SQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSI----GRKHCGTALFSGIYTRVS 382
            ...|..|:.||.:|:|||||.:..|   .||..:|  .|:||.    |.......|...:||.|:
Mosquito   200 EMFCGKGQNGVSACNGDSGGGMFFE---VSGRWFV--RGLVSFTPARGSSGLCDPLKYTVYTDVA 259

  Fly   383 SYMDWIESTI 392
            .|::||:..|
Mosquito   260 KYVEWIKQYI 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	66/264 (25%)
		Tryp_SPc	133..391	CDD:238113	68/267 (25%)
AgaP_AGAP000411	XP_001237291.3	Tryp_SPc	23..267	CDD:238113	68/266 (26%)
		Tryp_SPc	25..265	CDD:214473	66/264 (25%)
		Tryp_SPc	308..>462	CDD:304450
		Trypsin	838..1069	CDD:278516
		Tryp_SPc	864..>946	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910