DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP012778

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001230340.2	Gene:	AgaP_AGAP012778 / 4397620	VectorBaseID:	AGAP012778	Length:	276	Species:	Anopheles gambiae

Alignment Length:	273	Identity:	76/273 - (27%)
Similarity:	116/273 - (42%)	Gaps:	52/273 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI-HTMGRNLTAAI 190
            |.|.|::||  :.:....|...:. |.|:|.....||.:.|.::|:||||||: :.....:..||
Mosquito    38 AGSQRIIGG--SAVTAPSWMVAVG-EVVNGNWSNFCGGTLIDKQWVLTAAHCVANAQSGPMEVAI 99

  Fly   191 LGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQY-----SELNYR-----NDIALLRLS 245
                             ||.:.:.||.|..:|::|.|.:|     |.|.||     :|:|||.|:
Mosquito   100 -----------------GVSDLSRPHTRSKVDQVLMHPEYYVNLLSNLGYRETPYSSDVALLHLA 147

  Fly   246 RPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA 310
            .||      ...|:.:.....:...|...:.....|:|......:....|...:.:..:.: ::.
Mosquito   148 TPV------TQAPIVMADITTKDTWQWNTTMLHAIGYGGINPDATKSSPQLLAVDLAYRGE-RDY 205

  Fly   311 FYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFS 375
            :|.|...|    .:.||...|.|:|.||||||||.      |.:   |.||.|.|...|.|....
Mosquito   206 WYGDPTTT----HIFAGKLAGQDTCKGDSGGPLTY------GGK---LVGVTSYGAFPCATGSAG 257

  Fly   376 GIYTRVSSYMDWI 388
            | ||...::.|||
Mosquito   258 G-YTYAPAFSDWI 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	72/267 (27%)
		Tryp_SPc	133..391	CDD:238113	73/267 (27%)
AgaP_AGAP012778	XP_001230340.2	Tryp_SPc	42..269	CDD:214473	72/267 (27%)
AgaP_AGAP012778	XP_001230340.2	Tryp_SPc	43..269	CDD:238113	71/266 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910