DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG9733

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	143/451 - (31%)
Similarity:	202/451 - (44%)	Gaps:	90/451 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLLIPLFLTLL---GAEAQQFGKAIMHFGNCNSVEFGRGTCIEKKDCD-FYAVDKLMELASKQQ 61
            |.:...:||.:|   .|:||...:.:    |.|...   |.|:...:|. .|:|.|...|..:::
  Fly     1 MKVFAAVFLCILIAHEAKAQSDSRCL----NPNQTP---GLCVLINECQTLYSVLKRATLTDQEK 58

  Fly    62 CF---------SRQRPDLVCCPRETNII-----------------------PP--LAPR-----I 87
            .|         |..:| .|||.::|..:                       |.  :.||     .
  Fly    59 SFIKSSACGRGSNNQP-YVCCTQDTGYVRIQRQDRTFPDYGAFGGDWEEERPQSFVFPRQERRPW 122

  Fly    88 SNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGS-AFSFRLVGGHNTGLFEFPWTTLLEY 151
            |.|...|||.|      |........|...||:.|.||. ....|:..|.:|.:.||||..||||
  Fly   123 SFGNQPATSRT------PFRKSSTSDGSSLLPQPPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEY 181

  Fly   152 ETVSG-GKDYACGASFIAQRWLLTAAHCIHTMGR------NLTAAILGEWNRDTDPDCENDLNGV 209
            ...|| |...||..|.|.:|::||||||:  .||      .|.:..|||.:..|..||.   .|.
  Fly   182 RRRSGNGLSTACAGSLINRRYVLTAAHCL--TGRIEREVGTLVSVRLGEHDTRTAVDCP---PGG 241

  Fly   210 RECAPPHIRVTIDRILPHAQYSE--LNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQL 272
            ..|:|...|:..:.|..|.:|||  .|..:||.|:|:.|.|.:  ..|::|:|||...|..:.|
  Fly   242 GSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIRMERNVRY--SDNIQPICLPSSVGLESRQ- 303

  Fly   273 AGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGVDSCSG 337
            :|....|:|||:|.....|.:|||..::.....:|::.| ...|:.|..:|:||||:...|||.|
  Fly   304 SGQQFTVAGWGRTLKMARSAVKQKVTVNYVDPAKCRQRF-SQIKVNLEPTQLCAGGQFRKDSCDG 367

  Fly   338 DSGGPLTVEANTASGNRY----VYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIRA 394
            ||||||.         |:    ..|.|:||.|.| ||...:.|:||.|::|..||...:||
  Fly   368 DSGGPLM---------RFRDESWVLEGIVSFGYK-CGLKDWPGVYTNVAAYDIWIRQNVRA 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/54 (24%)
		Tryp_SPc	131..388	CDD:214473	100/269 (37%)
		Tryp_SPc	133..391	CDD:238113	101/270 (37%)
CG9733	NP_651784.2	CLIP	25..78	CDD:288855	13/60 (22%)
		Tryp_SPc	161..412	CDD:214473	100/269 (37%)
		Tryp_SPc	162..415	CDD:238113	101/271 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5140
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25969
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.930