DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG10232

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	116/398 - (29%)
Similarity:	176/398 - (44%)	Gaps:	104/398 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FGNCNSVEFGRGTCIEKKDCDFYAVDKLME----LASKQQC-FSRQRPD-----LVCCPRETNII 80
            |.:|.:.|    .||....| ....:..||    |...:|| ...:|.|     .:|||...|::
  Fly   185 FPDCPADE----KCIRLDKC-LRIHNTTMEDGANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVL 244

  Fly    81 PPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFS-FRLVGGHNTGLFEFP 144
            |             ||                           ||.|.. :|:..|......|:|
  Fly   245 P-------------TS---------------------------CGQAPPLYRMAYGTAARPNEYP 269

  Fly   145 WTTLLEYE-----TVSGGKDYACGASFIAQRWLLTAAHCI--HTMGRN---LTAAILGEWNRDTD 199
            |..:|.||     |::..    |..|.|.:|::||||||:  ..|...   |....|||.:..|:
  Fly   270 WMAMLIYENRRLSTMTNN----CSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTN 330

  Fly   200 PDCENDLNGVRECAPPHIRVTIDRILPHAQY-SELNYRNDIALLRLSRPVNWLQMQNLEPVCLPP 263
            |||  |..|  .||.|.:.:.|:....|.|| :...:.:||||:||..||.:  ...:.|:|:|
  Fly   331 PDC--DFTG--NCAAPFVEIGIEYFNVHEQYFNTSRFESDIALVRLQTPVRY--THEILPICVP- 388

  Fly   264 QRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLH---IQPQDQCQE--AFYKDTKITLADSQ 323
               :....|......::|||.|::...|::    :||   .:.:..||:  :|:::      :||
  Fly   389 ---KDPIPLHNHPLQIAGWGYTKNREYSQV----LLHNTVYENRYYCQDKISFFRN------ESQ 440

  Fly   324 MCAGGEIGVDSCSGDSGGPLTVEANTASGNRY---VYLAGVVSIGRKHCGTALFSGIYTRVSSYM 385
            :||.|..|.|||.|||||||.:..|    |.|   |||||:||.|.::||... .|:||:..::.
  Fly   441 ICASGIRGEDSCEGDSGGPLMLTLN----NDYQDIVYLAGIVSYGSENCGDRK-PGVYTKTGAFF 500

  Fly   386 DWIESTIR 393
            .||::.::
  Fly   501 SWIKANLK 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/54 (24%)
		Tryp_SPc	131..388	CDD:214473	91/275 (33%)
		Tryp_SPc	133..391	CDD:238113	92/276 (33%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	92/274 (34%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	90/271 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5140
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	1	1.000	-	-		FOG0003849
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920