DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG3505

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	128/409 - (31%)
Similarity:	196/409 - (47%)	Gaps:	72/409 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLIPLFLTLLGAEAQQFGKAIMHFGNC-NSVEFGR--GTCIEKKDCDFYAVDKL--------MEL 56
            ||:.:....|||.||      :...|| ..:..||  |.||..::||::....|        ..|
  Fly     7 LLVVVGSLALGANAQ------LPPINCVAKIPSGRVTGHCISIRECDYFMRILLSGNLSQSDRNL 65

  Fly    57 ASKQQCFSRQRPDLVCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEH 121
            ....||..|.....||||                      ||..|..|  |.|..||.
  Fly    66 LRDNQCGVRGNDVQVCCP----------------------STAGLGAL--THPLLPSD------- 99

  Fly   122 PYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI---HTMG 183
              ||.. .::.....:|.:.||||..|:||...:..|.:|||...|:.|::||||||:   .|..
  Fly   100 --CGKV-RWQRSNDTDTRIREFPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSN 161

  Fly   184 RNLTAAILGEWNRDTDPDCE-NDLNGVRECAPPHIRVTIDRILPHAQYSELNYR--NDIALLRLS 245
            ..:||..||||:..|:|||: ::.:.|.:||||:..:.|:.:|||..|:..:..  |||||:||:
  Fly   162 LQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLA 226

  Fly   246 RPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA 310
            .|......  ::|:|||.::.| |::|.....:|:||    .:.||:..:|..:.|...::||..
  Fly   227 SPAKLNDF--VQPICLPNKQLR-ADELEDLVTEVAGW----QASSSQRMRKGYVTISSIEECQRK 284

  Fly   311 FYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFS 375
             |...::.:..|::|  |......|.|::||||.:..|    :.|: |.|:||.|...|....:.
  Fly   285 -YASQQLRIQASKLC--GLTNSQECYGNAGGPLMLFKN----DGYL-LGGLVSFGPVPCPNPDWP 341

  Fly   376 GIYTRVSSYMDWIESTIRA 394
            .:||||:||:|||..:::|
  Fly   342 DVYTRVASYIDWIHDSLKA 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	15/55 (27%)
		Tryp_SPc	131..388	CDD:214473	90/262 (34%)
		Tryp_SPc	133..391	CDD:238113	92/263 (35%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855	13/51 (25%)
		Tryp_SPc	111..356	CDD:238113	92/259 (36%)
		Tryp_SPc	111..354	CDD:214473	90/257 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I5140
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	1	1.000	-	-		FOG0003849
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920