DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG12951

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	78/284 - (27%)
Similarity:	117/284 - (41%)	Gaps:	77/284 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGR----------- 184
            |:|.|.::.:.::|:...|.    |....::||.|.|::.:::|||||  |.||
  Fly    29 RVVNGTDSSVLKYPFVVSLR----SYDGSHSCGGSIISKHFVMTAAHC--TNGRPADTLSIQFGV 87

  Fly   185 -NLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYR-NDIALLRLSRP 247
             |::|  :|                      |:: |.|.:|:.|..:...... |||:||.:..|
  Fly    88 TNISA--MG----------------------PNV-VGIKKIIQHEDFDPTRQNANDISLLMVEEP 127

  Fly   248 VNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA-- 310
            ..: ...::.||.||..........||....:.|||..::.||            .||..||.
  Fly   128 FEF-DGVSVAPVELPALAFAVPQSDAGVEGVLIGWGLNDTYGS------------VQDTLQEVSL 179

  Fly   311 -FYKDTKITLADS-------QMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGR 366
             .|.|.:.|...:       .:|.| .|.|...|||||||||......         .|:||...
  Fly   180 KIYSDEECTSRHNGQTDPKYHICGGVDEGGKGQCSGDSGGPLIYNGQQ---------VGIVSWSI 235

  Fly   367 KHCGTALFSGIYTRVSSYMDWIES 390
            |.|..|.:.|:|.:||.|:|||:|
  Fly   236 KPCTVAPYPGVYCKVSQYVDWIKS 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	75/280 (27%)
		Tryp_SPc	133..391	CDD:238113	77/282 (27%)
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	75/280 (27%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	77/283 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455954
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930