DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss45

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001008864.1	Gene:	Prss45 / 408244	RGDID:	1303021	Length:	330	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	90/303 - (29%)
Similarity:	138/303 - (45%)	Gaps:	49/303 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LKLLPRTTPRPPSGIDQLPEHPYCGSA-FSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGA 164
            |.|||   |||..|.::....|.||:. :|..|...|:     :||...|:.|     .::.||.
  Rat    26 LLLLP---PRPNLGYNEDHAEPVCGAPWWSDSLEERHH-----WPWEVSLQIE-----NEHVCGG 77

  Fly   165 SFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQ 229
            :.|.|.|:::|||||  .|......:||  :....|      :|    :|..:::.:..|:.|.:
  Rat    78 ALIDQSWVVSAAHCI--QGNKEYLVMLG--SSTLQP------SG----SPWALKIPVGDIIMHPK 128

  Fly   230 YSELNY-RNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKI 293
            |...|: |:|||||.|..||.:  .:.::|:|||...   .|...|....|:|||:.:...|:|:
  Rat   129 YWGQNFIRSDIALLCLETPVTF--NKYIQPICLPEHN---FNLKVGMKCWVTGWGQAKQHPSAKL 188

  Fly   294 KQ-----KAMLHIQPQDQCQEAFYKDT----KITLADSQMCAGGEIGVDSCSGDSGGPLTVEANT 349
            .:     :|.:.|.....|...|:|.|    .|.|....|........:.|.||.||||..|.:
  Rat   189 TRSLELWEAEVSIVDNKNCDRVFHKKTFYPQVIPLIRKNMICTTNHRENPCYGDPGGPLACEVH- 252

  Fly   350 ASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
               .|:: |||:.| ..|.|..|....:|||:..|..||:..:
  Rat   253 ---GRWI-LAGIFS-WEKACTKAPNLSVYTRIDKYTGWIKEQV 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	76/266 (29%)
		Tryp_SPc	133..391	CDD:238113	77/267 (29%)
Prss45	NP_001008864.1	Tryp_SPc	57..289	CDD:238113	77/266 (29%)
Prss45	NP_001008864.1	Tryp_SPc	57..286	CDD:214473	75/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910