DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and prss29

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001001228.1	Gene:	prss29 / 407909	XenbaseID:	XB-GENE-6453402	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	89/285 - (31%)
Similarity:	135/285 - (47%)	Gaps:	41/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 LPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM 182
            |....|.|...|.|:|||.::...|:||...||:|   ||  :.||.|.:...|:||||||..:|
Frog    12 LHHQAYGGPVMSKRIVGGTDSEEGEWPWQISLEFE---GG--FLCGGSLLTDSWVLTAAHCFDSM 71

  Fly   183 GRNLTAAILGEWNRDTDPDCEND-LNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSR 246
            ..:...|.||.:...   |.:|. |.||:       .:|:     |..|.......||||:.|..
Frog    72 NVSKYTAYLGVYQLS---DLDNAVLRGVK-------NITV-----HPDYMYEGSSGDIALIELEE 121

  Fly   247 PVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESS---GSSKIKQKAMLHIQPQDQCQ 308
            |:  :...:::|||||.|.   .....|:...|:|||..:.:   ...:..|||.:.:..:..|:
Frog   122 PI--VFTPSIQPVCLPSQD---VPLPMGTMCWVTGWGNIKENTPLEDPQTLQKAEVGLINRTSCE 181

  Fly   309 EAF-----YKDTKITLADSQMCAGGEIG-VDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRK 367
            ..:     |:.:...:.|..:|||.:.| :|:|.|||||||.  .||:  |.::.. |:||.| .
Frog   182 AMYQSSLGYRPSIHLIQDDMICAGYKQGKIDACQGDSGGPLV--CNTS--NTWLQF-GIVSWG-L 240

  Fly   368 HCGTALFSGIYTRVSSYMDWIESTI 392
            .|......|:||.|..|:.||:..:
Frog   241 GCAEPNQPGVYTNVQYYLTWIQELV 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/266 (31%)
		Tryp_SPc	133..391	CDD:238113	84/267 (31%)
prss29	NP_001001228.1	Tryp_SPc	26..263	CDD:238113	84/267 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910