DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and ovch1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_956439.2	Gene:	ovch1 / 393114	ZFINID:	ZDB-GENE-040426-834	Length:	556	Species:	Danio rerio

Alignment Length:	268	Identity:	84/268 - (31%)
Similarity:	130/268 - (48%)	Gaps:	41/268 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGR-NLTAAILGEW 194
            |::||.......:||...|:|..|.     .||.:.:.|.|::||.||.....: ::..|::|..
Zfish    56 RIIGGKEAWAHSWPWQVSLQYNDVP-----TCGGAILDQLWVITAGHCFKRYKKPSMWNAVVGLH 115

  Fly   195 NRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPV 259
            |.|      |.....||      .:.:.:|..|..|::....||||||:|..|:.:.:.  :.|:
Zfish   116 NLD------NANESSRE------SIQVQKIFSHKNYNQKTNENDIALLKLQSPLVFSKF--VRPI 166

  Fly   260 CLPPQRGRYANQLAG-SAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAFYKDTKITLAD 321
                  |.:.|.|.. ....|:|||....:|  :|::::..:...:|| :|.. ||:.   .:..
Zfish   167 ------GVFNNDLPPLVTCTVTGWGSVTENGPQASRLQEVNVTVYEPQ-KCNR-FYRG---KVLK 220

  Fly   322 SQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYM 385
            |.:||| .|.|:|:|.|||||||    :...|.|| .||||||.| ..||.|...|:||.:..|.
Zfish   221 SMICAGANEGGMDACQGDSGGPL----SCFDGERY-KLAGVVSWG-VGCGRAQKPGVYTTLYHYR 279

  Fly   386 DWIESTIR 393
            .|:.|::|
Zfish   280 QWMVSSMR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	81/261 (31%)
		Tryp_SPc	133..391	CDD:238113	81/262 (31%)
ovch1	NP_956439.2	Tryp_SPc	56..281	CDD:214473	81/260 (31%)
		Tryp_SPc	57..281	CDD:238113	80/259 (31%)
		Tryp_SPc	331..551	CDD:238113
		Tryp_SPc	331..549	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910