DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and teq

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	107/429 - (24%)
Similarity:	164/429 - (38%)	Gaps:	118/429 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EAQQFGKA--------IMHFGN------CNSVEFGRGTCIEKKDCDFYAVDKLMELASKQQCFSR 65
            |...||.:        :|.|||      ||...:|...|...:|...:             |.:.
  Fly  2431 EKNIFGNSNGPIWLDQVMCFGNETSIDQCNHWNWGEHNCNHTEDVALH-------------CSAG 2482

  Fly    66 QRPDLVCCPRETNIIPPLAPRIS----NGTTNATSSTTTLKLLPRT---------------TPRP 111
            .              ||.:.|.|    .|..:....||     |:|               |||
  Fly  2483 P--------------PPRSQRYSQTQIKGGRSLGRETT-----PKTYSQIGLWERSSKAVHTPR- 2527

  Fly   112 PSGI---DQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLL 173
            ..||   |...|:.:...    |:|.|:.......||...:......|...:.|||..|::|.||
  Fly  2528 RCGIFKDDLTDEYAHREE----RVVRGNVAQRGRHPWQATIRTRGRGGISSHWCGAVVISKRHLL 2588

  Fly   174 TAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYR-- 236
            |||||::...:......:|:...:.....|                 :|..:.: .|...|:|
  Fly  2589 TAAHCLYGSPKGAYFVRVGDHYANIAESSE-----------------VDSFIEN-WYLHENFRKG 2635

  Fly   237 ----NDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTES--SGSSKIKQ 295
                |||||:.|..|:.:  ...::|:|||.:.   |..:......:||||..:|  |..:::..
  Fly  2636 THMNNDIALVVLKTPLKF--SDYVQPICLPDKN---AELVEDRKCTISGWGSIKSGVSTPAQVLG 2695

  Fly   296 KAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLA 359
            .|.|.|.....|:::....:  .:::...|||. :..||:|.|||||||     ..|.:....|.
  Fly  2696 SAELPILADHVCKQSNVYGS--AMSEGMFCAGSMDESVDACEGDSGGPL-----VCSDDDGETLY 2753

  Fly   360 GVVSIGRKHCGTALFSGIYTRVSSYMDWI-----ESTIR 393
            |::|.| :|||.....|:|.||:.|:|||     ||.:|
  Fly  2754 GLISWG-QHCGFKNRPGVYVRVNHYIDWIYEKINESLLR 2791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	6/44 (14%)
		Tryp_SPc	131..388	CDD:214473	73/265 (28%)
		Tryp_SPc	133..391	CDD:238113	75/271 (28%)
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060
		SR	2229..2331	CDD:214555
		SRCR	2234..2332	CDD:278931
		LDLa	2337..2370	CDD:197566
		SR	2382..2480	CDD:214555	12/61 (20%)
		SRCR	2386..2480	CDD:278931	12/61 (20%)
		Tryp_SPc	2546..2781	CDD:214473	73/265 (28%)
		Tryp_SPc	2547..2784	CDD:238113	74/267 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010