DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG6462

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	74/277 - (26%)
Similarity:	117/277 - (42%)	Gaps:	35/277 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 SAFSFRLVGGH--NTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTA 188
            :|...|:.||.  ..|:|.:....:::   :||.....||.|.|..:::||||||       ||.
  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQ---LSGADLVKCGGSLITLQFVLTAAHC-------LTD 125

  Fly   189 AILGE--WNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
            ||..:  .......|.|:.:.        .::||....:.:..|......:|:||:||.|.|.
  Fly   126 AIAAKIYTGATVFADVEDSVE--------ELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVR-- 180

  Fly   252 QMQNLEPVCLPPQRGRYANQ--LAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKD 314
            ..:.::|:.|   .|.:.:|  |.|....:||||....|...:.:....|..:..||.:...|..
  Fly   181 TSEQVQPIEL---AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFL 242

  Fly   315 TKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYT 379
            ..:......:|..|..|..:|:||||||:.......|     ||.||.|.|...........:||
  Fly   243 PGLVSQRRHLCTDGSNGRGACNGDSGGPVVYHWRNVS-----YLIGVTSFGSAEGCEVGGPTVYT 302

  Fly   380 RVSSYMDWI-ESTIRAN 395
            |:::|:.|| :.|...|
  Fly   303 RITAYLPWIRQQTAMTN 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	69/262 (26%)
		Tryp_SPc	133..391	CDD:238113	70/264 (27%)
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	69/262 (26%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910