DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and mas

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_523919.1	Gene:	mas / 38499	FlyBaseID:	FBgn0011653	Length:	1047	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	87/280 - (31%)
Similarity:	129/280 - (46%)	Gaps:	47/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAI--LGE 193
            |:|||.:....|:.|...|    ::....|.|||:.|..:|:||||||:..:.|:..|..  :|:
  Fly   802 RVVGGEDGENGEWCWQVAL----INSLNQYLCGAALIGTQWVLTAAHCVTNIVRSGDAIYVRVGD 862

  Fly   194 WNRDTDPDCENDLNGVRECAPP---HIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQN 255
            :          ||  .|:...|   .:||....|  |..::.....||||||:|..     |.:.
  Fly   863 Y----------DL--TRKYGSPGAQTLRVATTYI--HHNHNSQTLDNDIALLKLHG-----QAEL 908

  Fly   256 LEPVCLP--PQRGRYANQLAGSAADVSGWGKTESSGSSKIK-QKAMLHIQPQDQCQEAFYKDTKI 317
            .:.|||.  |.||  .:..||....|:|:|....:|...:: ::|.:.|....:|   ..|...:
  Fly   909 RDGVCLVCLPARG--VSHAAGKRCTVTGYGYMGEAGPIPLRVREAEIPIVSDTEC---IRKVNAV 968

  Fly   318 T-----LADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGI 377
            |     |..|..|||||.|.|:|.||.||||..:     .:.:..|||:||.| ..||.....|:
  Fly   969 TEKIFILPASSFCAGGEEGHDACQGDGGGPLVCQ-----DDGFYELAGLVSWG-FGCGRQDVPGV 1027

  Fly   378 YTRVSSYMDWIESTIRANRI 397
            |.:.||::.||...|..|.:
  Fly  1028 YVKTSSFIGWINQIISVNNL 1047

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/269 (31%)
		Tryp_SPc	133..391	CDD:238113	84/270 (31%)
mas	NP_523919.1	Tryp_SPc	803..1041	CDD:238113	84/271 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940