DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG1299

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	113/382 - (29%)
Similarity:	168/382 - (43%)	Gaps:	64/382 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CNSVEFGRGTCIEKKDCDFYAVDKLMELASKQQ------------CFSRQRPDLVCCPRETNIIP 81
            |...:...|.|:|.|:|    ...|.||.|:.|            ...:.:...||||
  Fly   164 CRGPDTKPGNCVEIKEC----ASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCP------- 217

  Fly    82 PLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSF--RLVGGHNTGLFEFP 144
                 ...|.||.|.:.:  :::|:.|...|..:..:.|.  |||...:  ::|||..:....:|
  Fly   218 -----TGQGITNTTPAPS--QIVPKNTDEIPRRLLNVEEG--CGSTVGYFKKIVGGEVSRKGAWP 273

  Fly   145 WTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGV 209
            |..||.|:..| |..:.||.:.|..|.:|||||||.   ::|....|||.:..||.:
  Fly   274 WIALLGYDDPS-GSPFKCGGTLITARHVLTAAHCIR---QDLQFVRLGEHDLSTDTE-------- 326

  Fly   210 RECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAG 274
                ..|:.:.|.|.:.|..|:..|.|:|:|:|.|.|.|.:  ...:.|:|||...........|
  Fly   327 ----TGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEF--TSKIAPICLPHTANLRQKSYVG 385

  Fly   275 SAADVSGWGKTESSG-SSKIKQKAMLHIQPQDQCQEAFYKDTKITLAD----SQMCAG---GEIG 331
            ....|:|||||...| |:::..:..:.|.....|.:::.|:.:...||    :.:|||   |  |
  Fly   386 YMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSG--G 448

  Fly   332 VDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            .|:|.|||||||.: .....|....||.||||.| ..|......|:|:....:||||
  Fly   449 KDTCQGDSGGPLML-PEPYQGQLRFYLIGVVSYG-IGCARPNVPGVYSSTQYFMDWI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	13/56 (23%)
		Tryp_SPc	131..388	CDD:214473	85/264 (32%)
		Tryp_SPc	133..391	CDD:238113	87/264 (33%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/55 (22%)
		Tryp_SPc	260..503	CDD:214473	85/264 (32%)
		Tryp_SPc	261..503	CDD:238113	85/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920