DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG14990

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	101/332 - (30%)
Similarity:	144/332 - (43%)	Gaps:	74/332 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 APRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGG------HNT-GLF 141
            ||.|.||    .|.|..|:      |.|         :..||.:....||..      ::| |
  Fly    27 APGIFNG----MSFTENLQ------PDP---------NQVCGMSNPNGLVANVKVPKDYSTPG-- 70

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAIL--GEWNRDTDPDCEN 204
            :|||...|    .|.||.:..| |.||...:||||..:  :|:.....::  ||||
  Fly    71 QFPWVVAL----FSQGKYFGAG-SLIAPEVVLTAASIV--VGKTDAEIVVRAGEWN--------- 119

  Fly   205 DLNGVR-ECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRY 268
              .|.| |..|...| .:.|::.|.::|.|...|:||||.|:.|..  ...::..:|||.| ||.
  Fly   120 --TGQRSEFLPSEDR-PVARVVQHREFSYLLGANNIALLFLANPFE--LKSHIRTICLPSQ-GRS 178

  Fly   269 ANQLAGSAADVSGWGKT--ESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKI----TLADSQMCAG 327
            .:|   ....|:||||.  .....|.|::|..|.:..:.|||:.. ::|::    .|..|.:|||
  Fly   179 FDQ---KRCLVTGWGKVAFNDENYSNIQKKIELPMINRAQCQDQL-RNTRLGVSFDLPASLICAG 239

  Fly   328 GEIGVDSCSGDSGGPL--TVEANTASGNRYVYLAGVVS--IGRKHCGTALFSGIYTRVSSYMDWI 388
            ||.....|.||.|..|  .:||:.   :||.. ||:|:  ||   |.......:||.|..:.|||
  Fly   240 GEKDAGDCLGDGGSALFCPMEADP---SRYEQ-AGIVNWGIG---CQEENVPAVYTNVEMFRDWI 297

  Fly   389 ESTIRAN 395
            ...:..|
  Fly   298 YEHMAQN 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	86/276 (31%)
		Tryp_SPc	133..391	CDD:238113	87/277 (31%)
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	86/267 (32%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	84/264 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910