DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and flz

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	109/358 - (30%)
Similarity:	156/358 - (43%)	Gaps:	63/358 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 KQQCFSRQRP---DLVCCPRETNIIP-PLAPRISNGTT------------NATSSTTTLKLLPRT 107
            |....|..||   ::|....|.::.| |....|..|.|            ::||.|.....|...
  Fly  1368 KTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGANGRKIHSTSRTLPTPNLAFH 1432

  Fly   108 TPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSG--GKDYACGASFIAQR 170
            :|....|:     .|:..|.   |:|||..:....:||..|:...|..|  .|: .||...|..|
  Fly  1433 SPSTECGV-----RPHVKSG---RIVGGKGSTFGAYPWQVLVRESTWLGLFTKN-KCGGVLITSR 1488

  Fly   171 WLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNY 235
            :::|||||......:| .|::||:      |...||...|.     :...:.|::.|.||....:
  Fly  1489 YVITAAHCQPGFLASL-VAVMGEF------DISGDLESKRS-----VTKNVKRVIVHRQYDPATF 1541

  Fly   236 RNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLA---GSAADVSGWGKTE-SSGSSKIKQK 296
            .||:|||.|..||.:  ..::.|:|:|       |.:|   |..|.|:|||:.: ..|...:.|:
  Fly  1542 ENDLALLELDSPVQF--DTHIVPICMP-------NDVADFTGRMATVTGWGRLKYGGGVPSVLQE 1597

  Fly   297 AMLHIQPQDQCQEAFY---KDTKITLADSQMCAGGEIG-VDSCSGDSGGPLTVEANTASGNRYVY 357
            ..:.|.....|||.|:   .:.||  ..|.:|||...| .|||.|||||||.::   ....|| .
  Fly  1598 VQVPIIENSVCQEMFHTAGHNKKI--LTSFLCAGYANGQKDSCEGDSGGPLVLQ---RPDGRY-E 1656

  Fly   358 LAGVVSIGRKHCGTALFSGIYTRVSSYMDWIES 390
            |||.||.|.| |......|:|.|.:.|..|:.|
  Fly  1657 LAGTVSHGIK-CAAPYLPGVYMRTTFYKPWLRS 1688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	5/17 (29%)
		Tryp_SPc	131..388	CDD:214473	88/266 (33%)
		Tryp_SPc	133..391	CDD:238113	89/268 (33%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	89/269 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910