DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG14760

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	94/330 - (28%)
Similarity:	136/330 - (41%)	Gaps:	71/330 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 TSSTTTLK------LLPRTTPRPPSG---IDQLPE--HPYCGSAFSF--RLVGGHN--TGLFEFP 144
            :||.|:.|      ..|...|.|..|   ...|.|  .|.|...:|.  |:....|  ..|.|||
  Fly   225 SSSKTSAKRARIVSSYPTAAPSPGHGGGRFSCLVEAFQPTCSCGWSRIPRIASPTNEEAVLHEFP 289

  Fly   145 WTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAA-----ILGEWNRDTDPDCEN 204
              .:....|...||.: |||:.|..|:||:||||.  :|....:|     ::|          |:
  Fly   290 --PMAGVLTKKHGKVF-CGAAIIHHRYLLSAAHCF--LGPETNSAAKLRVVVG----------EH 339

  Fly   205 DLNGVRECAPPHIRVTIDRILPHAQYSELN--YRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGR 267
            ||....|..... |..:|.::.|..:|:.:  .:||||:|:....:.|  .|::.|.|||.|.|.
  Fly   340 DLASSFETFATQ-RYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVW--SQHVGPACLPLQPGE 401

  Fly   268 YANQ--LAGSAADVSGWGKTESSGSSKIK-QKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG- 328
            ...:  |||.....:|||.|...|....: .||.|.:....:|::|.            ..|||
  Fly   402 DGQKLPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQAL------------SSAGGL 454

  Fly   329 --------EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYM 385
                    ..|.|:|..||||.|....|..     :...|:||.|:. | .|....:.|||:|::
  Fly   455 PPHTFCTYTPGRDTCQYDSGGALYERINGR-----LMAVGIVSFGQA-C-AAQQPSVNTRVASFI 512

  Fly   386 DWIES 390
            .||.:
  Fly   513 KWIRT 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	79/277 (29%)
		Tryp_SPc	133..391	CDD:238113	80/279 (29%)
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	78/271 (29%)
		Tryp_SPc	281..515	CDD:214473	77/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940