DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Corin

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	98/357 - (27%)
Similarity:	154/357 - (43%)	Gaps:	59/357 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 PDLVC------CPRETNIIPPLAPRISNGTTNATSSTTTLKLLPR---TTPRPPSGIDQLPEHPY 123
            |..||      ....|:::..|..|....|.|.  ||...|:..:   |..:..:...:..::|.
  Fly  1018 PSAVCSILGYSAVNATSVLTQLTHRPLLATVNV--STDIWKMYAKRKSTLMQEFANCKKTEDYPM 1080

  Fly   124 ---------CGSAF------SFRLVGGHNTGLFEFPWTTLLEYETVSGG--KDYACGASFIAQRW 171
                     ||...      |.|::||.......:|:..     .:.||  |.:.|....|:.:|
  Fly  1081 ADLTCSNYECGRVKRGRHKPSRRIIGGTQASPGNWPFLA-----AILGGPEKIFYCAGVLISDQW 1140

  Fly   172 LLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS-ELNY 235
            :|||:||:    .|.:...|.:|.........|......:      :|.:..::||.||: .:.:
  Fly  1141 VLTASHCV----GNYSVIDLEDWTIQLGVTRRNSFTYSGQ------KVKVKAVIPHPQYNMAIAH 1195

  Fly   236 RNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTE----SSGSSKIKQK 296
            .|||||.:|:..|.:  .::|.||||||...|  |...|:...|.||||.|    .|....|..:
  Fly  1196 DNDIALFQLATRVAF--HEHLLPVCLPPPSVR--NLHPGTLCTVIGWGKREDKDPKSTYEYIVNE 1256

  Fly   297 AMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAG 360
            ..:.|..::||.|  :.| .:|:::..:||| .:.|.|:|.|||||||.. ......||: ::.|
  Fly  1257 VQVPIITRNQCDE--WLD-NLTVSEGMVCAGFDDGGKDACQGDSGGPLLC-PYPGEKNRW-FVGG 1316

  Fly   361 VVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            :||.|.. |......|:|..|..|:.||:..|
  Fly  1317 IVSWGIM-CAHPRLPGVYANVVQYVPWIQEQI 1347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	3/11 (27%)
		Tryp_SPc	131..388	CDD:214473	79/264 (30%)
		Tryp_SPc	133..391	CDD:238113	80/265 (30%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555	3/15 (20%)
		SRCR	992..1086	CDD:278931	13/69 (19%)
		Tryp_SPc	1103..1343	CDD:214473	79/264 (30%)
		Tryp_SPc	1104..1346	CDD:238113	80/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910