DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss21

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006245934.1	Gene:	Prss21 / 353251	RGDID:	727870	Length:	337	Species:	Rattus norvegicus

Alignment Length:	345	Identity:	101/345 - (29%)
Similarity:	147/345 - (42%)	Gaps:	62/345 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCG-SAFSFRLVGGHNT 138
            |...::|.|...::   ...|..:|:..:.|....:|......|...| || .....|:|||...
  Rat     4 RGKTLVPLLVVVVA---VEVTLQSTSSHVKPVDPEKPELQEANLLSGP-CGHRTIPSRIVGGEEA 64

  Fly   139 GLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCE 203
            .|..:||...|.   |.|  ::.|||:.:.:||:||||||               :.:|.||...
  Rat    65 ELGRWPWQGSLR---VWG--NHLCGATLLNRRWVLTAAHC---------------FQKDNDPFDW 109

  Fly   204 NDLNGVRECAPP-------HIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCL 261
            ....|.....|.       ..|..|:.|....:|:| .:.:|||||:||.||.:...  ::|:||
  Rat   110 TVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYTE-QFPHDIALLKLSSPVTYSNF--IQPICL 171

  Fly   262 PPQRGRYANQLAGSAADVSGW---GKTESSGSSKIKQKAMLHIQPQDQCQEAFYK-DTKITLADS 322
            .....::||:   :...|:||   |:.||.......|:..:.|.....|...|.| |.:|.:...
  Rat   172 LNSTYKFANR---TDCWVTGWGAIGEDESLPLPNNLQEVQVAIINNTMCNHLFKKPDFRINIWGD 233

  Fly   323 QMCAGG-EIGVDSC---------SGDSGGPLTVEANTASGNRYVYLAGVVS--IGRKHCGTALFS 375
            .:|||. |.|.|:|         .|||||||....:|.     .|..||||  ||   ||.....
  Rat   234 MVCAGSPEGGKDACFAKLTYAAPQGDSGGPLVCNQDTV-----WYQVGVVSWGIG---CGRPNRP 290

  Fly   376 GIYTRVSSYMDWIESTIRAN 395
            |:||.:|.:.:||..|:..|
  Rat   291 GVYTNISHHYNWIRLTMIRN 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	86/279 (31%)
		Tryp_SPc	133..391	CDD:238113	87/280 (31%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	86/279 (31%)
Prss21	XP_006245934.1	Tryp_SPc	58..304	CDD:238113	86/279 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910