DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CG4650

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_609722.2	Gene:	CG4650 / 34859	FlyBaseID:	FBgn0032549	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	71/280 - (25%)
Similarity:	108/280 - (38%)	Gaps:	48/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTA 188
            ||     .|..|........||...|....:.    |.||.:.|.::.:||||||  |.......
  Fly    28 CG-----LLTNGKIANNISSPWMAYLHTSELL----YVCGGTVITEKLVLTAAHC--TRASEQLV 81

  Fly   189 AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQM 253
            |.:||: ..||...:..|:          ...:.:...|:.|:.....||||:|.|:..:  :..
  Fly    82 ARIGEF-IGTDDANDTMLS----------EYQVSQTFIHSLYNTTTSANDIAILGLATDI--VFS 133

  Fly   254 QNLEPVCLP--PQRGRYANQ---LAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYK 313
            :.:.|:|:.  ....:|.:.   |:|:.     ||.......|...:...:..||.:.|...
  Fly   134 KTIRPICIVWWTIWRKYIDNIQVLSGAQ-----WGLPNDRNESDAFRITDIRRQPANMCSTL--- 190

  Fly   314 DTKITLADSQMCAGGEIGVDS--CSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSG 376
             ....:..||.|||..   ||  |:.|...||.......:..||| |.|:.:..:| |..|   .
  Fly   191 -NGTAILSSQFCAGDS---DSKLCNVDFSSPLGAIITFKNIQRYV-LIGIATTNQK-CKRA---S 246

  Fly   377 IYTRVSSYMDWIESTIRANR 396
            :||.|.|:.|:|.|..|..|
  Fly   247 VYTDVLSHTDFILSVWRQYR 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	65/263 (25%)
		Tryp_SPc	133..391	CDD:238113	65/264 (25%)
CG4650	NP_609722.2	Tryp_SPc	33..258	CDD:214473	64/260 (25%)
CG4650	NP_609722.2	Tryp_SPc	33..258	CDD:304450	64/260 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910