DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and ela2l

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_956180.1	Gene:	ela2l / 334304	ZFINID:	ZDB-GENE-040511-1	Length:	267	Species:	Danio rerio

Alignment Length:	271	Identity:	83/271 - (30%)
Similarity:	128/271 - (47%)	Gaps:	43/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDY-ACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEW 194
            |:|||.:.....:||...|:|:  ||...| .||.|.|.::|:|||||||.:  .......||:.
Zfish    28 RVVGGVDVRPNSWPWQISLQYK--SGSNWYHTCGGSLIDKQWVLTAAHCISS--SRTYRVFLGKH 88

  Fly   195 NRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPV 259
            :      ...:.||       .:.:...:|:.|..::....||||||::|...|.  ....:.|.
Zfish    89 S------LSQEENG-------SVAIGAGKIIVHEAWNSFTIRNDIALIKLETAVT--IGDTITPA 138

  Fly   260 CLPPQRGRYANQLAG------SAADVSGWGKTESSGS-SKIKQKAMLHIQPQDQCQEAFYKDTKI 317
            |||.         ||      :...|:|||:..::|. :.|.|:|:|.:.....|.::.:..:::
Zfish   139 CLPE---------AGYVLPHNAPCYVTGWGRLYTNGPLADILQQALLPVVDHATCSKSDWWGSQV 194

  Fly   318 TLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGR-KHCGTALFSGIYTRV 381
            |  .|.:||||:..|..|.|||||||    |.|..:....:.|:||.|. ..|.......::|||
Zfish   195 T--TSMVCAGGDGVVAGCDGDSGGPL----NCAGSDGAWEVHGIVSFGSGLSCNYNKKPTVFTRV 253

  Fly   382 SSYMDWIESTI 392
            |:|.|||...:
Zfish   254 SAYSDWISKNM 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	81/265 (31%)
		Tryp_SPc	133..391	CDD:238113	82/266 (31%)
ela2l	NP_956180.1	Tryp_SPc	28..260	CDD:214473	81/265 (31%)
ela2l	NP_956180.1	Tryp_SPc	29..263	CDD:238113	82/267 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910