DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP012817

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_560999.5	Gene:	AgaP_AGAP012817 / 3292527	VectorBaseID:	AGAP012817	Length:	439	Species:	Anopheles gambiae

Alignment Length:	290	Identity:	70/290 - (24%)
Similarity:	117/290 - (40%)	Gaps:	49/290 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWT--TLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNL 186
            ||:.....|..|....|   ||.  .|.:.|.|.      |..:.|::.:::..|.|.....::|
Mosquito   180 CGTKSETVLDNGQPAPL---PWLGFVLTKEEKVK------CVVTLISEWYVVGTASCFEKNEKDL 235

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
             ..:.|.:....:..| .:.||...||.|....:|.|::.|.::|:....::|||:.|..|.:..
Mosquito   236 -RILFGGYEDLLEQKC-FERNGSTVCAYPTQSRSIGRVVAHPRFSKNTINDNIALIELQSPADTT 298

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-------SSKIKQKAMLHIQPQDQCQE 309
            | .:::|:|||.....|.|             :||:..       :..|..:::.|:.| |.|:.
Mosquito   299 Q-PHVKPICLPVTPTLYTN-------------RTENFSVLAFRLTTGTIVDQSVNHVDP-DFCKS 348

  Fly   310 -----AFYKDTKITLADSQMCAG-GEIGVDSCSG--DSGGPLTVEANTA-SGNRYVYLAGVVSIG 365
                 .|..|.:    :...|.. .|..|.:|..  ..|.||....:.. :|.||| |.|...:|
Mosquito   349 VHIVAGFAIDNE----EKSFCVSVPEEDVANCDSLLGQGTPLQEHVSMVNAGERYV-LRGFDLLG 408

  Fly   366 RKHCGTALFSGIYTRVSSYMDWIESTIRAN 395
            ....|.:....:|..|.||:||:...:|.|
Mosquito   409 LTCAGDSSIPVLYVNVYSYLDWMLYNMRYN 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	65/274 (24%)
		Tryp_SPc	133..391	CDD:238113	65/275 (24%)
AgaP_AGAP012817	XP_560999.5	Tryp_SPc	<1..150	CDD:238113
		Tryp_SPc	190..430	CDD:214473	63/270 (23%)
		Tryp_SPc	190..430	CDD:304450	63/270 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910