DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP009006

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_552907.3	Gene:	AgaP_AGAP009006 / 3291875	VectorBaseID:	AGAP009006	Length:	401	Species:	Anopheles gambiae

Alignment Length:	379	Identity:	85/379 - (22%)
Similarity:	137/379 - (36%)	Gaps:	101/379 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CNSVEFGRGTCIEKKDCDFYAVDKLMELASKQQCFSRQRPDLVCCPRETNIIPPLAPRISNGTTN 93
            |.:.:...|.|:....|...|:.|.:    .:.|.:...| :||||                 .|
Mosquito   101 CEASDREAGVCVHIDHCSHRALAKDV----VKVCTNETAP-IVCCP-----------------VN 143

  Fly    94 ATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFS-FR-----LVGGHNTGL----FEFPWTTL 148
            :..:|..|.||..                 |.:.:. ||     .||...|..    ...|.:.:
Mosquito   144 SFIATAHLPLLTE-----------------CETNYQRFRKKYADFVGDRGTAQPLEDGAHPHSVM 191

  Fly   149 LEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECA 213
            :.::.......:.|..:.|....:||.|.|.:.:.       :||.|          :..:.:.|
Mosquito   192 IGWKVNKTATAWHCTGTLINLNTVLTTAGCANMVS-------VGETN----------VARIYDGA 239

  Fly   214 PPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAAD 278
            ...|||  ...:.:..|:...:.||||:|:|...|  |..:|..|.||    .|..|:......:
Mosquito   240 AQIIRV--KETIRYPSYNAKTHDNDIAVLKLESDV--LVNENAIPACL----WRDLNRTPYYGQE 296

  Fly   279 VSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMC--------AGGEIGVDSC 335
            |...|:     |...:.|.::|   ...|| .|...|::|  :.|:|        .|.:  ..:|
Mosquito   297 VHFDGQ-----SLTARDKNVVH---NRDCQ-LFTSHTELT--NDQLCWQEFRLRPDGAD--APNC 348

  Fly   336 SGDSGGPLTVEANTASGNRYV-YLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
             |..|.|......|  .|.|: ||.|:.|..|:..|....  :.||:|||::||
Mosquito   349 -GRKGNPFITLQRT--NNIYLPYLVGLYSYDRQCAGGEPI--VATRISSYINWI 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	10/44 (23%)
		Tryp_SPc	131..388	CDD:214473	64/274 (23%)
		Tryp_SPc	133..391	CDD:238113	65/269 (24%)
AgaP_AGAP009006	XP_552907.3	Tryp_SPc	<1..64	CDD:304450
		Tryp_SPc	184..398	CDD:304450	62/257 (24%)
		Tryp_SPc	184..397	CDD:214473	60/255 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910