DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP008997

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_319746.4	Gene:	AgaP_AGAP008997 / 3291872	VectorBaseID:	AGAP008997	Length:	248	Species:	Anopheles gambiae

Alignment Length:	272	Identity:	100/272 - (36%)
Similarity:	145/272 - (53%)	Gaps:	44/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGG---KDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILG 192
            |:||||::|....||...|    :..|   |..:||.:.|:.||::|||||:.|   ||... ||
Mosquito     7 RIVGGHSSGFGTHPWQAAL----IKSGFLTKKLSCGGALISNRWVVTAAHCVAT---NLKVR-LG 63

  Fly   193 EWN-RDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNL 256
            ||: ||            :|....|...:|:|...|..||..::||||||::|.|.|  :..|::
Mosquito    64 EWDVRD------------QEERLTHEEYSIERKEVHPNYSPSDFRNDIALVKLDRKV--VFRQHI 114

  Fly   257 EPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSS--KIKQKAMLHIQPQDQCQEAF-YKDTKIT 318
            .||||||:    :.:|.|..|.|:|||:|....|:  .:.|:..:.:.|.::||..| ....:.|
Mosquito   115 LPVCLPPK----SVKLVGKMATVAGWGRTRHGQSTVPSVLQEVDVEVIPNERCQRWFRAAGRRET 175

  Fly   319 LADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVS--IGRKHCGTALFSGIYTR 380
            :.|..:||| .|.|.|||.||||||||:   :..|.:  .|.|:||  ||   ||.....|:||.
Mosquito   176 IHDVFLCAGYKEGGRDSCQGDSGGPLTL---SIEGRK--TLIGLVSWGIG---CGREHLPGVYTN 232

  Fly   381 VSSYMDWIESTI 392
            :..::.|||..:
Mosquito   233 IQKFVPWIEKVM 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	97/266 (36%)
		Tryp_SPc	133..391	CDD:238113	99/267 (37%)
AgaP_AGAP008997	XP_319746.4	Tryp_SPc	7..240	CDD:214473	97/266 (36%)
AgaP_AGAP008997	XP_319746.4	Tryp_SPc	8..243	CDD:238113	99/268 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910