DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and TRY3_ANOGA

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_317171.2	Gene:	TRY3_ANOGA / 3291693	VectorBaseID:	AGAP008294	Length:	268	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	83/285 - (29%)
Similarity:	121/285 - (42%)	Gaps:	53/285 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 RTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQR 170
            |..|||...:             ..|:|||....:.|.|:...|:|     ...:.||.|.:..:
Mosquito    29 RFLPRPKYDV-------------GHRIVGGFEIDVSETPYQVSLQY-----FNSHRCGGSVLNSK 75

  Fly   171 WLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNY 235
            |:||||||...:..:..|..||....                |.....|.:.|:|.|..|.:...
Mosquito    76 WILTAAHCTVNLQPSSLAVRLGSSRH----------------ASGGTVVRVARVLEHPNYDDSTI 124

  Fly   236 RNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKAML 299
            ..|.:|:.|...:.:..:  ::||.||.|.....:   |:...|||||.|:|:. |:.|.:.|.:
Mosquito   125 DYDFSLMELESELTFSDV--VQPVSLPDQDEAVED---GTMTIVSGWGNTQSAAESNAILRAANV 184

  Fly   300 HIQPQDQCQEAFYKDTKITLADSQMCAGGEI-GVDSCSGDSGGPLTVEANTASGNRYVYLAGVVS 363
            ....|.:|..|:.....||  |..:|||.:. |.|:|.|||||||.|:..         |.||||
Mosquito   185 PTVNQKECTIAYSSSGGIT--DRMLCAGYKRGGKDACQGDSGGPLVVDGK---------LVGVVS 238

  Fly   364 IGRKHCGTALFSGIYTRVSSYMDWI 388
            .| ..|....:.|:|.||:...||:
Mosquito   239 WG-FGCAMPGYPGVYARVAVVRDWV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/258 (30%)
		Tryp_SPc	133..391	CDD:238113	78/258 (30%)
TRY3_ANOGA	XP_317171.2	Tryp_SPc	41..262	CDD:214473	78/258 (30%)
TRY3_ANOGA	XP_317171.2	Tryp_SPc	42..265	CDD:238113	78/259 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910