DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP011917

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_552323.2	Gene:	AgaP_AGAP011917 / 3291454	VectorBaseID:	AGAP011917	Length:	246	Species:	Anopheles gambiae

Alignment Length:	260	Identity:	59/260 - (22%)
Similarity:	110/260 - (42%)	Gaps:	42/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWN 195
            |:|||.:....:.||...|.    :....:.||.:.::.|::|::|:|:.......|.|:.|...
Mosquito    23 RIVGGIDAVAGDAPWMVSLR----NSINQHLCGGTLLSNRFVLSSANCLSGRLATATMAVAGSRF 83

  Fly   196 RDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVC 260
            .:|             .|.|:..:   :|:.|..::.....:|:||.:.:  :.::..|:::|:.
Mosquito    84 LNT-------------AAIPYYGI---QIITHPNFNVNTLEHDVALFQTA--LQFILTQSVQPLP 130

  Fly   261 LPPQRGRYANQL-AGSAADVSGWGKTESS-GSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQ 323
            |.      |:.: .|..|.|.|||.:::: |::...|...::....|.|.. |.......:..|.
Mosquito   131 LS------ADVIGVGVRARVFGWGASQANGGNTNALQFLNVNTLSNDDCAN-FLGAEGWRIGPSS 188

  Fly   324 MCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            :|.....|...|.||.||.|.::.         |..||.|.|.. |.|.. ..::.|:|:...||
Mosquito   189 LCTLTREGQGICGGDEGGALVLDN---------YAIGVASWGIP-CATGR-PDVFVRISAVRSWI 242

Fly 389 388
Mosquito 243 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	57/258 (22%)
		Tryp_SPc	133..391	CDD:238113	58/258 (22%)
AgaP_AGAP011917	XP_552323.2	Tryp_SPc	23..242	CDD:214473	57/258 (22%)
AgaP_AGAP011917	XP_552323.2	Tryp_SPc	24..242	CDD:238113	56/257 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910