DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and CLIPB3

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_307750.3	Gene:	CLIPB3 / 3290783	VectorBaseID:	AGAP003249	Length:	365	Species:	Anopheles gambiae

Alignment Length:	403	Identity:	141/403 - (34%)
Similarity:	195/403 - (48%)	Gaps:	70/403 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PLFLTLLGAEAQQFGKAIMHFGNCNSV-EFGR-GTCIEKKDCDFYAV----------DKLMELAS 58
            |||..||.......|..:    |.|.| ..|. |.||..::|.....          |.|  |.:
Mosquito    16 PLFFVLLWMVHSVVGLDL----NVNCVTPLGESGKCILFRECQPLITIYNKPINTHDDTL--LLT 74

  Fly    59 KQQCFSRQRPDLVCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPY 123
            :.:|...||..|||||               .|:.|.||                    |||.|.
Mosquito    75 QSRCGMLQRKTLVCCP---------------VTSQARSS--------------------LPEPPV 104

  Fly   124 CGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM--GRNL 186
            ||...:.|::||..|.:.|||||.|:|::...|...:.||.|.|..|:::||||||.::  |..:
Mosquito   105 CGIHLADRVIGGQPTQIDEFPWTALIEFQKPDGSFGFHCGGSLINDRYIVTAAHCIKSIPRGWKV 169

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQY--SELNYRNDIALLRLSRPVN 249
            ....||||:..:..||:|:.     |:...|.:.|::|:.|..|  .:.:..|||||:|.:||||
Mosquito   170 HRVRLGEWDLTSANDCQNEF-----CSDAPIDLDIEQIVVHTGYDTKDQSNANDIALIRFTRPVN 229

  Fly   250 WLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKD 314
            :  .|.:.|:|||..........||..|..:|||||||:.:|:.|.|..::|:...:|... |:.
Mosquito   230 Y--SQTVRPICLPLSSSLRNRNHAGMPAYAAGWGKTESATASEKKLKVEMNIKSLQECAPV-YQR 291

  Fly   315 TKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYT 379
            ..|.|..:.|||||..|.|:|||||||||   ....||:  .||.||||.|.:.||.....|:||
Mosquito   292 GGILLKKTHMCAGGVRGKDTCSGDSGGPL---MRQMSGS--WYLIGVVSFGPQKCGAPGVPGVYT 351

  Fly   380 RVSSYMDWIESTI 392
            .|:.|:|||:..|
Mosquito   352 NVAEYVDWIKDNI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	16/56 (29%)
		Tryp_SPc	131..388	CDD:214473	103/260 (40%)
		Tryp_SPc	133..391	CDD:238113	104/261 (40%)
CLIPB3	XP_307750.3	CLIP	37..89	CDD:288855	14/53 (26%)
		Tryp_SPc	112..360	CDD:214473	103/260 (40%)
		Tryp_SPc	113..363	CDD:238113	104/262 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880