DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005687

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_556332.3	Gene:	AgaP_AGAP005687 / 3290023	VectorBaseID:	AGAP005687	Length:	297	Species:	Anopheles gambiae

Alignment Length:	295	Identity:	86/295 - (29%)
Similarity:	127/295 - (43%)	Gaps:	39/295 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 RPPSGIDQL-----PE-HPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIA 168
            ||....|..     || ..|.....:.|:|.|......:||:...|......|  ...||.|.:.
Mosquito    29 RPVEEFDHYWARLPPELQVYRNDTSTDRVVNGQEALPGQFPYQVALLLNFPDG--TALCGGSVLT 91

  Fly   169 QRWLLTAAHCIHTMGRNLTA---AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQY 230
            :.::||||||:......|.:   ||:|..||.           ..|.:...||.|...|..|.:|
Mosquito    92 RNFILTAAHCVSATSTTLVSGGIAIMGAHNRT-----------AMELSQQRIRFTSTGIRRHPEY 145

  Fly   231 SELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKI 293
            .:.:.|||:||:.|:.|:.:  ...::|:.||.:..  ..|..|....|||:|::..:.  .|.|
Mosquito   146 DDTSLRNDVALILLNSPMTF--TSRVKPISLPARTD--TRQFEGFTGTVSGFGRSSDASPYPSSI 206

  Fly   294 KQKAMLHIQPQDQCQEAFYKDTKITLADSQ-MCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVY 357
            .:.....|..:.:|..::    ...||.|| :|.....|..||:|||||||||.    ||.  |.
Mosquito   207 LRFTSNPIMSKAECIVSW----GFALAQSQNVCLKPTGGRSSCNGDSGGPLTVN----SGG--VL 261

  Fly   358 LAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            ..|.||.|..:...:.:..:|.|||.::.||...|
Mosquito   262 QIGTVSFGSSYGCASGWPSVYARVSYFLSWINENI 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	77/262 (29%)
		Tryp_SPc	133..391	CDD:238113	78/263 (30%)
AgaP_AGAP005687	XP_556332.3	Tryp_SPc	56..292	CDD:214473	77/262 (29%)
AgaP_AGAP005687	XP_556332.3	Tryp_SPc	57..295	CDD:238113	78/264 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910