DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005663

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_556312.2	Gene:	AgaP_AGAP005663 / 3290018	VectorBaseID:	AGAP005663	Length:	317	Species:	Anopheles gambiae

Alignment Length:	297	Identity:	88/297 - (29%)
Similarity:	131/297 - (44%)	Gaps:	77/297 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 QLPEHPYCGSAFSFRLVGGHNTGLFEFPW--TTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI 179
            :||.|         |:..|......:||:  ..|..:.|.:|    .||.|.:...::||||||:
Mosquito    67 KLPSH---------RITNGQEATPGQFPYQIALLSNFATGTG----LCGGSVLTNNYILTAAHCV 118

  Fly   180 HTMGRNLT---AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIAL 241
            .:....|.   .||:|..||:           |.|.....|..|...|..|..|:..|.|||||:
Mosquito   119 ISGATTLATSGTAIMGAHNRN-----------VNEPTQQRIGFTSAGIRAHPGYNPTNIRNDIAV 172

  Fly   242 LRLSRPVNWLQMQNLEPVCLPPQRGRY-ANQLAGSAADVSGWGKTESSGSSK------------- 292
            :||:.|:.:  ...::|:.||   ||. :.|..|....|||:|:|.::|::.
Mosquito   173 VRLNSPITF--TARIQPIRLP---GRSDSRQFGGFTGTVSGFGRTTNTGATSPVVMFTSNPVMTN 232

  Fly   293 ---IKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNR 354
               |.:.....||||:                  :|..|:.|..||:|||||||||:   ..|:.
Mosquito   233 ADCIARWNTALIQPQN------------------VCLSGDGGRSSCNGDSGGPLTVQ---DGGSL 276

  Fly   355 YVYLAGVVSIG-RKHCGTALFSGIYTRVSSYMDWIES 390
            .:   |:||.| ...|...:.| :|.|||.|:|||::
Mosquito   277 QI---GIVSFGSAAGCSIGMPS-VYARVSFYLDWIDA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	83/279 (30%)
		Tryp_SPc	133..391	CDD:238113	84/281 (30%)
AgaP_AGAP005663	XP_556312.2	Tryp_SPc	72..307	CDD:214473	83/279 (30%)
AgaP_AGAP005663	XP_556312.2	Tryp_SPc	73..310	CDD:238113	84/282 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910