DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP005665

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_556314.2	Gene:	AgaP_AGAP005665 / 3290017	VectorBaseID:	AGAP005665	Length:	300	Species:	Anopheles gambiae

Alignment Length:	280	Identity:	85/280 - (30%)
Similarity:	124/280 - (44%)	Gaps:	42/280 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 QLPEHPYCGSAFSFRLVGGHNTGLFEFPW--TTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI 179
            :||.|         |:|.|......:||:  ..|..:.|.:|    .||.|.:...::||||||:
Mosquito    49 KLPSH---------RIVNGQEATPGQFPYQIALLSNFPTGTG----LCGGSVLTNNYILTAAHCV 100

  Fly   180 HTMGRNLT---AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIAL 241
            .:....|.   .||:|..|||           |.|.:...|..:...|..|..|:..|.|||||:
Mosquito   101 ISGASTLALGGTAIIGAHNRD-----------VAEPSQQRIAFSTAGIRAHPGYTLTNIRNDIAV 154

  Fly   242 LRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQ 306
            :||:.|:.:  ...::|..||.:..  ..|..|....|||:|:| |..|.......|....|...
Mosquito   155 VRLNSPITF--TDRIQPARLPARSD--TRQFGGFTGTVSGFGRT-SDASQATSSVVMFTTNPVLT 214

  Fly   307 CQEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGT 371
            ..:...:...:.:....:|..|..|..||:|||||||.|:   ..|:..|   ||||.| ...|.
Mosquito   215 NADCIAQWNAVVIEPQNVCLSGAGGRSSCNGDSGGPLAVQ---DGGSLQV---GVVSFG-SAAGC 272

  Fly   372 AL-FSGIYTRVSSYMDWIES 390
            |: ...:|.|||.::|:||:
Mosquito   273 AIGMPSVYARVSFFLDFIEA 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/262 (31%)
		Tryp_SPc	133..391	CDD:238113	81/264 (31%)
AgaP_AGAP005665	XP_556314.2	Tryp_SPc	54..290	CDD:214473	80/262 (31%)
AgaP_AGAP005665	XP_556314.2	Tryp_SPc	55..293	CDD:238113	81/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910